Evidence map›Paper›PMID 34708557›Full record

ArticleImmunity, inflammation and disease2022

Comparative clinical characteristics among different age group of adult COVID-19 patients: A multicenter study.

Wei Cheng, Yating Peng, Aiyuan Zhou, Ling Lin, Xin Liao, Dingding Deng, Peng Huang, Wenlong Liu, Mingyan Jiang, Xudong Xiang and 4 more

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Immunity, inflammation and disease, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 1 country.

Wei ChengDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Yating PengDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Aiyuan ZhouDepartment of Pulmonary and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ling LinDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Xin LiaoDepartment of Respiratory Medicine, Affiliated Shaoyang Central Hospital of University of South China, Shaoyang, Hunan, China.
Dingding DengDepartment of Respiratory Medicine, The First Attached Hospital of Shaoyang University, Shaoyang, Hunan, China.
Peng HuangDepartment of Respiratory Medicine, Zhuzhou Central Hospital, Zhuzhou, Hunan, China.
Wenlong LiuDepartment of Respiratory Medicine, Yueyang Second People's Hospital, Designated Hospital of Junshan District, Yueyang, Hunan, China.
Mingyan JiangDepartment of Respiratory and Critical Medicine, Xiangtan Central Hospital, Xiangtan, Hunan, China.
Xudong XiangDepartment of Emergency Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Qingcui ShuangDepartment of Respiratory Medicine, The First Attached Hospital of Shaoyang University, Shaoyang, Hunan, China.
Shan CaiDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Ping ChenDepartment of Respiratory and Critical Care Medicine, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.ORCID 0000-0001-6707-8636
Xucai LiaoDepartment of Respiratory Medicine, The First Attached Hospital of Shaoyang University, Shaoyang, Hunan, China.
Central South University · CNShaoyang University · CNXiangyang Central Hospital · CNYueyang Second People's Hospital · CN

Funding

National Natural Science Foundation of China 81770046National Natural Science Foundation of China 81970044Xiangya Mingyi grant 2013
6 · The paper itself

Abstract

backgroundCoronavirus disease (COVID-19) is a global infectious disease with a large burden of illness and high health care costs. This study aimed to compare clinical features among adult COVID-19 patients in different age groups.

methodsLaboratory-confirmed adult COVID-19 infection cases between December 31, 2019 to March 8, 2020 obtained from Neighboring Cities. Patients were divided into five age groups. Clinical characteristics were compared among different age groups.

resultsOf 299 cases, median age was 44 and 158 (53%) were male. A total of 53.3% of 30-40 years, 50% of 40-50 years, 36.6% of <30 years and 36.2% of 50-60 years were primary case, none of the elderly were primary case. Among all the observed symptoms, only symptom of dyspnea was significantly different between the elderly group and other groups (p < .001). Proportion of severe or critical type was 2.4%, 5.3%, 9.5%, 14.5%, and 35% in patients with age <30, 30-40, 40-50, 50-65, ≥65, respectively. A total of 285 patients (95.3%) were cured and discharged, 12 patients (4.0%) were still on medical treatment in hospital. There were 2 (0.7%) deaths which occurred among persons ≥65 years. Patients with a history of chronic heart disease had a more than a 56 times higher risk for severe or critical type of COVID-19 than those without a history of chronic heart disease (odds ratio [OR]: 56.038, 95% confidence interval [CI]: 2.764-1136.053, p = .009). Old age (OR: 1.055, 95% CI: 1.016-1.095, p = .006), high heart rate in admission (OR: 1.085, 95% CI: 1.03-1.144, p = .002), high respiratory rate in admission (OR: 1.635, 95% CI: 1.093-2.431, p = .017) were independently associated with severe or critical type in COVID-19.

conclusionsProportion of severe or critical type increased with old age groups. Adults with old age and high heart rate, respiratory rate in admission and history of chronic heart disease were associated with severe or critical type in COVID-19.

Indexed as

COVID-19AdultAgedHospitalizationHumansMaleOdds RatioSARS-CoV-2ageCOVID-19criticalsevere

Identifiers

PMID34708557
PMCPMC8652767
OpenAlexW3208909234

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.