Evidence map›Paper›PMID 34708213›Full record

ArticleACS materials letters2020

Photothermal Intracellular Delivery Using Gold Nanodisk Arrays.

Chuanzhen Zhao, Tianxing Man, Xiaobin Xu, Qing Yang, Wenfei Liu, Steven J Jonas, Michael A Teitell, Pei-Yu Chiou, Paul S Weiss

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS materials letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Chuanzhen ZhaoDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0003-0162-1231
Tianxing ManDepartment of Mechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0001-5079-3844
Xiaobin XuDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0002-3479-0130
Qing YangDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0003-4422-5300
Wenfei LiuDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0003-1338-7905
Steven J JonasCalifornia NanoSystems Institute, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0002-8111-0249
Michael A TeitellCalifornia NanoSystems Institute, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0002-4495-8750
Pei-Yu ChiouDepartment of Mechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0003-4677-2447
Paul S WeissDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.ORCID 0000-0001-5527-6248
California NanoSystems Institute · USUniversity of California, Los Angeles · USTongji University · CN

Funding

Micro- to Nanoscale Neurochemical SensorsR01DA045550 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ANDREWS, ANNE MILASINCIC · 2017 to 2021
$5.8M
Nanoscience-Inspired Acoustofluidic Assembly Lines for Gene and Cellular TherapiesDP5OD028181 · OD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JONAS, STEVEN JOHN · 2019 to 2023
$1.9M
NIDA NIH HHS R01 DA045550NIH HHS DP5 OD028181
6 · The paper itself

Abstract

Local heating using pulsed laser-induced photothermal effects on plasmonic nanostructured substrates can be used for intracellular delivery applications. However, the fabrication of plasmonic nanostructured interfaces is hampered by complex nanomanufacturing schemes. Here, we demonstrate the fabrication of large-area plasmonic gold (Au) nanodisk arrays that enable photothermal intracellular delivery of biomolecular cargo at high efficiency. The Au nanodisks (350 nm in diameter) were fabricated using chemical lift-off lithography (CLL). Nanosecond laser pulses were used to excite the plasmonic nanostructures, thereby generating transient pores at the outer membranes of targeted cells that enable the delivery of biomolecules

Identifiers

PMID34708213
PMCPMC8547743
OpenAlexW3094181126

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.