Evidence map›Paper›PMID 34708207›Full record

ArticleBrain communications2021

Increased expression of GABA

Günther Sperk, Susanne Pirker, Elisabeth Gasser, Anna Wieselthaler, Anneliese Bukovac, Giorgi Kuchukhidze, Hans Maier, Meinrad Drexel, Christoph Baumgartner, Marin Ortler and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Cys-loop receptors on cannabinoids: All high?Frontiers in physiology · 2022
    Pooled it
  2. GABASynapse (New York, N.Y.) · 2026
    Review
  3. Review
  4. The role of GABANeuroscience and biobehavioral reviews · 2026
    Review
  5. Article
  6. GABACellular and molecular neurobiology · 2026
    Review
  7. Review
  8. Article
  9. Identification and quantification of GABAIBRO neuroscience reports · 2025
    Article
  10. Phenols and GABAFrontiers in pharmacology · 2024
    Review
  11. Article
  12. Virally-induced expression of GABAProgress in neurobiology · 2022
    Article
  13. FMRP regulates GABACell reports · 2022
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Günther SperkDepartment of Pharmacology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Susanne PirkerNeurological Department, Klinik Hietzing, 1130 Vienna, Austria.
Elisabeth GasserDepartment of Pharmacology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Anna WieselthalerDepartment of Pharmacology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Anneliese BukovacDepartment of Pharmacology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Giorgi KuchukhidzeDepartment of Neurology, Christian Doppler Klinik, Affiliated Member of the European Reference Network EpiCARE and Centre for Cognitive Neuroscience, Paracelsus Medical University of Salzburg, 5020 Salzburg, Austria.
Hans MaierINNPATH GmbH-Institute of Pathology, 6020 Innsbruck, Austria.
Meinrad DrexelDepartment of Pharmacology, Medical University of Innsbruck, 6020 Innsbruck, Austria.
Christoph BaumgartnerNeurological Department, Klinik Hietzing, 1130 Vienna, Austria.
Marin OrtlerDepartment of Neurosurgery, Klinik Landstrasse, Vienna Healthcare Network, 1030Vienna, Austria.
Thomas CzechDepartment of Neurosurgery, Medical University Vienna, 1090 Vienna, Austria.ORCID https://orcid.org/0000-0001-8112-2795
Innsbruck Medical University · ATKlinik Hietzing · ATMedical University of Vienna · ATUniversity of Salzburg · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Epilepsy animal models indicate pronounced changes in the expression and rearrangement of GABA

Indexed as

[3H]L-655,708alpha-5 subunitdentate gyrusGABAA receptor subunitshippocampus

Identifiers

PMID34708207
PMCPMC8545616
OpenAlexW3205010186

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.