Evidence map›Paper›PMID 34708114›Full record

ArticleERJ open research2021

Epidemiology and economic burden of bronchiectasis requiring hospitalisation in Singapore.

Hwee Pin Phua, Wei-Yen Lim, Ganga Ganesan, Joanne Yoong, Kelvin Bryan Tan, John Arputhan Abisheganaden, Albert Yick Hou Lim

Abstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Epidemiology of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. The hidden epidemic of post-tuberculosis bronchiectasis.African journal of thoracic and critical care medicine · 2023
    Article
  11. Review
  12. Article
  13. Observational
  14. Prevalence of bronchiectasis: a narrative review.Therapeutic advances in respiratory disease
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hwee Pin PhuaDept of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore.ORCID https://orcid.org/0000-0001-6531-8536
Wei-Yen LimDept of Clinical Epidemiology, Tan Tock Seng Hospital, Singapore.
Ganga GanesanInformation, Technology and Data Group, Ministry of Health Singapore, Singapore.
Joanne YoongCenter for Economic and Social Research, University of Southern California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0002-0162-9885
Kelvin Bryan TanInformation, Technology and Data Group, Ministry of Health Singapore, Singapore.
John Arputhan AbisheganadenDept for Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.
Albert Yick Hou LimDept for Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveLittle is known about the epidemiology and cost of bronchiectasis in Asia. This study describes the disease burden of bronchiectasis in Singapore.

methodsA nationwide administrative dataset was used to identify hospitalisations with bronchiectasis as a diagnosis. Population statistics and medical encounter data were used to estimate the incidence, mortality, prevalence and direct medical costs associated with bronchiectasis requiring hospitalisation.

resultsThere were 420 incident hospitalised bronchiectasis patients in 2017, giving an incidence rate of 10.6 per 100 000. Age-standardised incidence declined on average by 2.7% per year between 2007 and 2017. Incidence rates increased strongly with age in both men and women. Tuberculosis was a secondary diagnosis in 37.5% of incident hospitalisations in 2007, but has declined sharply since then. Patient survival was considerably lower in both men (5-year relative survival ratios (RSR) 0.63, 95% CI 0.59-0.66) and women (5-year RSR 0.75, 95% CI 0.72-0.78). The point prevalence of bronchiectasis was 147.1 per 100 000 in 2017, and increased sharply with age, with >1% of people aged ≥75 years having bronchiectasis. Total first-year costs among incident bronchiectasis patients in 2016 varied widely, with a mean±sd USD 7331±8863. Approximately 10% of the patients admitted in 2016 had total first-year costs of more than USD 14 380.

conclusionBronchiectasis is common and imposes a substantial burden on healthcare costs and survival rates of patients in Singapore.

Identifiers

PMID34708114
PMCPMC8542960

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.