Evidence map›Paper›PMID 34708111›Full record

ArticleERJ open research2021

Sputum procalcitonin: a potential biomarker in stable bronchiectasis.

William Good, Gene Jeon, Irene Zeng, Louanne Storey, Helen Qiao, Stuart Jones, Sarah Mooney, Lata Jayaram, David Holland, Conroy Wong

Open access · goldAbstract read
In one paragraph

Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. The importance of symptoms in bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2026
    Review
  2. Article
  3. Article
  4. Review
  5. Exacerbations of bronchiectasis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

William GoodDept of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-2656-1127
Gene JeonDept of Respiratory Medicine, Middlemore Hospital, Counties Manukau District Health Board, Otahuhu, Auckland, New Zealand.
Irene ZengDept of Mental Health and Addiction, Middlemore Hospital, Counties Manukau District Health Board, Otahuhu, Auckland, New Zealand.ORCID https://orcid.org/0000-0001-8100-3120
Louanne StoreyDept of Microbiology, Middlemore Hospital, Counties Manukau District Health Board, Otahuhu, Auckland, New Zealand.
Helen QiaoDept of Microbiology, Middlemore Hospital, Counties Manukau District Health Board, Otahuhu, Auckland, New Zealand.
Stuart JonesDept of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Sarah MooneyDept of Respiratory Medicine, Middlemore Hospital, Counties Manukau District Health Board, Otahuhu, Auckland, New Zealand.
Lata JayaramDept of Respiratory Medicine, Western Health, Melbourne, VIC, Australia.
David HollandDept of Infectious Diseases, Middlemore Hospital, Counties Manukau District Health Board, Otahuhu, Auckland, New Zealand.
Conroy WongDept of Medicine, Faculty of Medical and Health Sciences, The University of Auckland, Auckland, New Zealand.
Middlemore Hospital · NZUniversity of Auckland · NZThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sputum procalcitonin is elevated in exacerbations of bronchiectasis. The primary aim of this study was to investigate whether sputum procalcitonin levels are higher in patients with stable bronchiectasis than in healthy controls. We also assessed differences in procalcitonin levels in spontaneously expectorated and induced sputum samples and their repeatability 1 week later. Participants included were aged over 18 years and either had radiologically confirmed bronchiectasis or were healthy controls. Patients with bronchiectasis were clinically stable for at least 6 weeks and had spontaneous and induced sputum collected at visit 1 and again 7 days later. Only induced sputum samples were collected from healthy controls during visit 1. Sputum procalcitonin concentrations in sputum were measured. In total, 30 patients with bronchiectasis and 15 healthy controls were enrolled in this observational study. In the pooled data from visit 1 and 2, the geometric mean procalcitonin level in induced sputum was significantly higher in the bronchiectasis group than in the healthy control group (1.5 ng·mL

Identifiers

PMID34708111
PMCPMC8542939
OpenAlexW3191112759

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.