Evidence map›Paper›PMID 34708037›Full record

ReviewFrontiers in cell and developmental biology2021

The Roles of Non-coding RNA in the Development and Regeneration of Hair Follicles: Current Status and Further Perspectives.

Min Yang, Tingting Weng, Wei Zhang, Manjia Zhang, Xiaojie He, Chunmao Han, Xingang Wang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
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  7. Article
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  9. Article
  10. Review
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  13. iPSC-based approach for human hair follicle regeneration.Frontiers in cell and developmental biology · 2023
    Review
  14. Article
  15. Hirsutism, Normal Androgens and Diagnosis of PCOS.Diagnostics (Basel, Switzerland) · 2022
    Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Min YangDepartment of Burns & Wound Care Center, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Tingting WengDepartment of Burns & Wound Care Center, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Wei ZhangDepartment of Burns & Wound Care Center, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Manjia ZhangThe First Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China.
Xiaojie HeDepartment of General Practice, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Chunmao HanDepartment of Burns & Wound Care Center, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xingang WangDepartment of Burns & Wound Care Center, Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Second Affiliated Hospital of Zhejiang University · CNKey Laboratory of Guangdong Province · CNZhejiang Chinese Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alopecia is a common problem that affects almost every age group and is considered to be an issue for cosmetic or psychiatric reasons. The loss of hair follicles (HFs) and hair caused by alopecia impairs self-esteem, thermoregulation, tactile sensation and protection from ultraviolet light. One strategy to solve this problem is HF regeneration. Many signalling pathways and molecules participate in the morphology and regeneration of HF, such as Wnt/β-catenin, Sonic hedgehog, bone morphogenetic protein and Notch. Non-coding RNAs (ncRNAs), especially microRNAs and long ncRNAs, have significant modulatory roles in HF development and regeneration via regulation of these signalling pathways. This review provides a comprehensive overview of the status and future prospects of ncRNAs in HF regeneration and could prompt novel ncRNA-based therapeutic strategies.

Indexed as

alopeciahair folliclehair follicle cyclingnon-coding RNAregeneration

Identifiers

PMID34708037
PMCPMC8542792
OpenAlexW3206038043

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.