Evidence map›Paper›PMID 34708011›Full record

ArticleFrontiers in pediatrics2021

Longitudinal Trajectories of Hair Cortisol: Hypothalamic-Pituitary-Adrenal Axis Dysfunction in Early Childhood.

Cynthia R Rovnaghi, Joseph Rigdon, Jean-Michel Roué, Monica O Ruiz, Victor G Carrion, Kanwaljeet J S Anand

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Cynthia R RovnaghiPain/Stress Neurobiology Lab, Maternal and Child Health Research Institute, Stanford University School of Medicine, Stanford, CA, United States.
Joseph RigdonQuantitative Sciences Unit, Stanford University School of Medicine, Stanford, CA, United States.
Jean-Michel RouéDepartment of Pediatrics, University Hospital of Brest, Brest, France.
Monica O RuizDepartment of Pediatrics, Stanford University School of Medicine, Stanford, CA, United States.
Victor G CarrionDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA, United States.
Kanwaljeet J S AnandPain/Stress Neurobiology Lab, Maternal and Child Health Research Institute, Stanford University School of Medicine, Stanford, CA, United States.
Stanford University · US

Funding

Do Hair Cortisol and Hair Oxytocin represent the Stressful and Supportive Experiences of Preschool Children?R01HD099296 · NICHD · STANFORD UNIVERSITY · PI KANWALJEET S ANAND · 2019 to 2026
$5.8M
NICHD NIH HHS R01 HD099296
6 · The paper itself

Abstract

The objective of this study was to examine if longitudinal trajectories of hair cortisol concentrations (HCC) measured at two or three yearly time points can identify 1-3 year old children at risk for altered hypothalamic-pituitary-adrenal (HPA)-axis function due to early life stress (ELS). HCC was measured (

Indexed as

child developmentchronic stresscortisol trajectorieshair cortisol concentrationsHPA axis dysregulationhypothalamic-pituitary-adrenal axis

Identifiers

PMID34708011
PMCPMC8544285
OpenAlexW3205751091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.