Evidence map›Paper›PMID 34707924›Full record

ArticlePeerJ2021

Potential of artificial intelligence to accelerate diagnosis and drug discovery for COVID-19.

Indira Mikkili, Abraham Peele Karlapudi, T C Venkateswarulu, Vidya Prabhakar Kodali, Deepika Sri Singh Macamdas, Krupanidhi Sreerama

Abstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Indira MikkiliBiotechnology, Vignan's Foundation for Science, Technology & Research, Guntur, Andhra Pradesh, India.
Abraham Peele KarlapudiBiotechnology, Vignan's Foundation for Science, Technology & Research, Guntur, Andhra Pradesh, India.
T C VenkateswaruluBiotechnology, Vignan's Foundation for Science, Technology & Research, Guntur, Andhra Pradesh, India.
Vidya Prabhakar KodaliBiotechnology, Vikrama Simhapuri University, Nellore, Andhra Pradesh, India.
Deepika Sri Singh MacamdasBiotechnology, Vignan's Foundation for Science, Technology & Research, Guntur, Andhra Pradesh, India.
Krupanidhi SreeramaBiotechnology, Vignan's Foundation for Science, Technology & Research, Guntur, Andhra Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease (COVID-19) pandemic has caused havoc worldwide. The tests currently used to diagnose COVID-19 are based on real time reverse transcription polymerase chain reaction (RT-PCR), computed tomography medical imaging techniques and immunoassays. It takes 2 days to obtain results from the RT-PCR test and also shortage of test kits creating a requirement for alternate and rapid methods to accurately diagnose COVID-19. Application of artificial intelligence technologies such as the Internet of Things, machine learning tools and big data analysis to COVID-19 diagnosis could yield rapid and accurate results. The neural networks and machine learning tools can also be used to develop potential drug molecules. Pharmaceutical companies face challenges linked to the costs of drug molecules, research and development efforts, reduced efficiency of drugs, safety concerns and the conduct of clinical trials. In this review, relevant features of artificial intelligence and their potential applications in COVID-19 diagnosis and drug development are highlighted.

Indexed as

Artificial intelligenceComputed tomographyDrug discoveryHomology modelingMachine learningNeural networksPharmacogenomicsProtein predictionReverse transcriptase polymerase chain reactionSARS CoV-2

Identifiers

PMID34707924
PMCPMC8500072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.