Evidence map›Paper›PMID 34707878›Full record

ArticleRespirology case reports2021

Spontaneous improvement of interstitial pneumonia with autoimmune features: A case report.

Hirotsugu Ohkubo, Akiko Nakano, Kohei Fujita, Yoshiyuki Ozawa, Takayuki Murase, Akio Niimi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hirotsugu OhkuboDepartment of Respiratory Medicine, Allergy and Clinical Immunology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.ORCID https://orcid.org/0000-0002-8538-1150
Akiko NakanoDepartment of Respiratory Medicine, Allergy and Clinical Immunology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Kohei FujitaDepartment of Respiratory Medicine, Allergy and Clinical Immunology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Yoshiyuki OzawaDepartment of Radiology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Takayuki MuraseDepartment of Pathology and Molecular Diagnostics Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Akio NiimiDepartment of Respiratory Medicine, Allergy and Clinical Immunology Nagoya City University Graduate School of Medical Sciences Nagoya Japan.
Nagoya City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interstitial pneumonia with autoimmune features (IPAF) was proposed to describe patients with interstitial lung disease who do not meet the classification criteria for a defined connective tissue disease. Here, we report a spontaneous improvement case of IPAF. A 58-year-old man developed dry cough and dyspnoea. Positive result was obtained for the anti-centromere antibody. High-resolution computed tomography (HRCT) showed reticular abnormalities and ground-glass opacities. Cryobiopsy specimens revealed cellular non-specific interstitial pneumonia. The patient displayed periungual erythema and nail fold bleeding, but no sclerosis. He did not meet the criteria for systemic scleroderma, but did meet those for IPAF. Because symptoms slightly improved, the patient declined immunosuppressive treatment. After 6 months, repeated HRCT showed an apparent reduction in the area of ground-glass opacities. The forced vital capacity improved from 2.72 to 3.47 L and serum Krebs von den Lungen (KL)-6 decreased from 1977 to 531 U/ml, and symptoms disappeared.

Indexed as

interstitial pneumonia with autoimmune featuresnon‐specific interstitial pneumoniatransbronchial cryobiopsy

Identifiers

PMID34707878
PMCPMC8524667
OpenAlexW3211184194

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.