Evidence map›Paper›PMID 34707716›Full record

ArticleExperimental and therapeutic medicine2021

Isosinensetin alleviates the injury of human bronchial epithelial cells induced by PM

Yang Zou, Shuzhen Li, Xinming Li, Ye Sun, Mingyue Ma, Han Tian, Nan Wang, Jianhui Yuan, Chunling Xiao

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental and therapeutic medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yang ZouKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Shuzhen LiDepartment of Immunology, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Xinming LiKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Ye SunKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Mingyue MaKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Han TianKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Nan WangKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Jianhui YuanKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Chunling XiaoKey Lab of Environmental Pollution and Microecology of Liaoning Province, Shenyang Medical College, Shenyang, Liaoning 110034, P.R. China.
Shenyang Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flavonoids which are extracted from citrus peel and pulp have been reported to have multiple beneficial effects on human health. Isosinensetin (ISO) is a type of flavonoid compound, which has several protective effects including anticancer, antioxidant, antiviral, anti-inflammatory and bacteriostatic. However, the molecular mechanism of its antioxidant and anti-inflammatory effects remain unclear. The present study aimed to investigate the intervention effect and possible mechanism of ISO on human bronchial epithelial cells injured by fine particular matter ≤2.5 µm in diameter (PM

Indexed as

bronchial epithelial cellsfine particular matterinjuryisosinensetin

Identifiers

PMID34707716
PMCPMC8543438
OpenAlexW3205865088

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.