Evidence map›Paper›PMID 34707636›Full record

ArticleFrontiers in genetics2021

Genetic Risk Prediction of COVID-19 Susceptibility and Severity in the Indian Population.

P Prakrithi, Priya Lakra, Durai Sundar, Manav Kapoor, Mitali Mukerji, Ishaan Gupta, The Indian Genome Variation Consortium

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

P PrakrithiGenomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology, New Delhi, India.
Priya LakraDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi, India.
Durai SundarDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi, India.
Manav KapoorDepartment of Neuroscience, Icahn School of Medicine at Mt. Sinai, New York, NY, United States.
Mitali MukerjiGenomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology, New Delhi, India.
Ishaan GuptaDepartment of Biochemical Engineering and Biotechnology, Indian Institute of Technology Delhi, New Delhi, India.
The Indian Genome Variation ConsortiumGenomics and Molecular Medicine, CSIR Institute of Genomics and Integrative Biology, New Delhi, India.
Indian Institute of Technology Delhi · INInstitute of Genomics and Integrative Biology · INIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Host genetic variants can determine their susceptibility to COVID-19 infection and severity as noted in a recent Genome-wide Association Study (GWAS). Given the prominent genetic differences in Indian sub-populations as well as differential prevalence of COVID-19, here, we compute genetic risk scores in diverse Indian sub-populations that may predict differences in the severity of COVID-19 outcomes. We utilized the top 100 most significantly associated single-nucleotide polymorphisms (SNPs) from a GWAS by Pairo-Castineira et al

Indexed as

COVID-19genetic risk predictiongeneticsIndian populationpolygenic risk scoresuscepibility

Identifiers

PMID34707636
PMCPMC8543005
OpenAlexW3209577722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.