Evidence map›Paper›PMID 34707616›Full record

ArticleFrontiers in immunology2021

Mechanisms by Which Obesity Promotes Acute Graft-

Lam T Khuat, Logan V Vick, Eunju Choi, Cordelia Dunai, Alexander A Merleev, Emanual Maverakis, Bruce R Blazar, Arta M Monjazeb, William J Murphy

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Assessing the impact of nutritional status at allogeneic stem cell transplantation on clinical outcomes.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Translating MSC Therapy in the Age of Obesity.Frontiers in immunology · 2022
    Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lam T KhuatDepartment of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
Logan V VickDepartment of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
Eunju ChoiDepartment of Pathology, Microbiology and Immunology, School of Veterinary Medicine, University of California, Davis, Davis, CA, United States.
Cordelia DunaiDepartment of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
Alexander A MerleevDepartment of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
Emanual MaverakisDepartment of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
Bruce R BlazarMasonic Cancer Center and Division of Blood & Marrow Transplant & Cellular Therapy, Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States.
Arta M MonjazebDepartment of Radiation Oncology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
William J MurphyDepartment of Dermatology, School of Medicine, University of California, Davis, Sacramento, CA, United States.
University of California, Davis · USUniversity of Minnesota · US

Funding

Staff InvestigatorsP30CA093373 · NCI · UNIVERSITY OF CALIFORNIA DAVIS · PI Laura Marcu · 2002 to 2026
$84.9M
Trial Design and Biostatistical Support CoreP01CA065493 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Mark J Osborn · 1995 to 2026
$48.2M
Transgenic/KnockoutP01AI056299 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI SHARPE, ARLENE H. · 2003 to 2023
$42.5M
Enhancing Treg Therapeutic Efficacy in GVHDR01HL118979 · NHLBI · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, HIPPEN, KELI L · 2014 to 2025
$6.7M
T-CELL TARGETING FOR GVHDR01HL056067 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BLAZAR, BRUCE R · 1995 to 2022
$5.4M
In Vivo Prevention of Murine GVHDR37AI034495 · NIAID · UNIVERSITY OF MINNESOTA · PI Bruce R Blazar · 2017 to 2026
$5.4M
Multispecies Comparison of the Impact of Obesity on GVHD/GVTR01CA214048 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MURPHY, WILLIAM JOSEPH · 2017 to 2021
$3.2M
Exploiting the VISTA Pathway to Prevent Acute GVHD and Control Steroid Refractory DiseaseR01HL155114 · NHLBI · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R, NOELLE, RANDOLPH J. · 2021 to 2024
$2.7M
NCI NIH HHS P01 CA065493NCI NIH HHS P30 CA093373NCI NIH HHS R01 CA214048NHLBI NIH HHS R01 HL056067NHLBI NIH HHS R01 HL118979NHLBI NIH HHS R01 HL155114NIAID NIH HHS P01 AI056299NIAID NIH HHS R37 AI034495
6 · The paper itself

Abstract

The efficacy of allogeneic hematopoietic stem cell transplantation (allo-HSCT) is limited by the occurrence of acute and chronic graft-

Indexed as

AdiposityGastrointestinal MicrobiomeGraft vs Host DiseaseObesityAnimalsDiet, High-FatFemaleHematopoietic Stem Cell TransplantationMiceMice, Inbred BALB Ccytokine stormGVHDhigh-fat (HF) dietmicrobiomeobesity

Identifiers

PMID34707616
PMCPMC8542879
OpenAlexW3205990930

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.