Evidence map›Paper›PMID 34707615›Full record

ArticleFrontiers in immunology2021

Intranasal Vaccination With Recombinant Antigen-FLIPr Fusion Protein Alone Induces Long-Lasting Systemic Antibody Responses and Broad T Cell Responses.

Ming-Shu Hsieh, Chia-Wei Hsu, Ling-Ling Tu, Kit Man Chai, Li-Lu Yu, Chiao-Chieh Wu, Mei-Yu Chen, Chen-Yi Chiang, Shih-Jen Liu, Ching-Len Liao and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Mucosal Vaccination: A Promising Alternative Against Flaviviruses.Frontiers in cellular and infection microbiology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Ming-Shu HsiehNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Chia-Wei HsuNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Ling-Ling TuNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Kit Man ChaiNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Li-Lu YuNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Chiao-Chieh WuNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Mei-Yu ChenNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Chen-Yi ChiangNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Shih-Jen LiuNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Ching-Len LiaoNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
Hsin-Wei ChenNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan.
National Health Research Institutes · TWChina Medical University · TWKaohsiung Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A simple formulation is urgently needed for mucosal vaccine development. We employed formyl peptide receptor-like 1 inhibitory protein (FLIPr), an FcγR antagonist secreted by

Indexed as

Administration, IntranasalAnimalsAntigensBacterial ProteinsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesDendritic CellsImmunity, MucosalImmunoglobulin AImmunoglobulin GMiceMice, Inbred C57BLOvalbuminRecombinant Fusion ProteinsVaccinationAntigensBacterial ProteinsFPRL1 inhibitory protein, S aureusImmunoglobulin AImmunoglobulin GOvalbuminRecombinant Fusion ProteinsFcγ receptorformyl peptide receptor-like 1 inhibitory protein (FLIPr)intranasal vaccinationmucosal vaccinesZika vaccines

Identifiers

PMID34707615
PMCPMC8543008
OpenAlexW3207189374

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.