Evidence map›Paper›PMID 34707612›Full record

ReviewFrontiers in immunology2021

Microbiota-Gut-Brain Axis and Epilepsy: A Review on Mechanisms and Potential Therapeutics.

Manqiu Ding, Yue Lang, Hang Shu, Jie Shao, Li Cui

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 94 papers.

0numbers the graph read from it
0cells of the map it votes in
94citing papers in PubMed
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

94 citing papers in PubMed, 140 citations in OpenAlex.

  1. Trial
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  7. Holistic management of epilepsy in adults with intellectual development disorders.Epileptic disorders : international epilepsy journal with videotape · 2026
    Article
  8. Article
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  11. Article
  12. Review
  13. Article
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  17. Review
  18. Article
  19. Review
  20. Can bacteria control the human brain?Communicative & integrative biology · 2026
    Review

34 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Manqiu DingDepartment of Neurology, First Hospital of Jilin University, Changchun, China.
Yue LangDepartment of Neurology, First Hospital of Jilin University, Changchun, China.
Hang ShuDepartment of Neurology, First Hospital of Jilin University, Changchun, China.
Jie ShaoDepartment of Neurology, First Hospital of Jilin University, Changchun, China.
Li CuiDepartment of Neurology, First Hospital of Jilin University, Changchun, China.
Jilin University · CNFirst Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut-brain axis refers to the bidirectional communication between the gut and brain, and regulates intestinal homeostasis and the central nervous system

Indexed as

AnimalsBrainBrain-Gut AxisEpilepsyGastrointestinal MicrobiomeHumansNeuroimmunomodulationepilepsygut–brain axismicrobiotapathogenesistherapy

Identifiers

PMID34707612
PMCPMC8542678
OpenAlexW3206061592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.