Evidence map›Paper›PMID 34707610›Full record

ReviewFrontiers in immunology2021

New Insights on CD8

Rosaely Casalegno Garduño, Jan Däbritz

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.

  1. The role of CD8Frontiers in immunology · 2026
    Pooled it
  2. Pooled it
  3. Trial
  4. P2X7R+CD8αβiScience · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Coincident epithelial signals restrain commensal-specific CD8αβbioRxiv : the preprint server for biology · 2026
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Dysregulated immunometabolism in gut inflammation.Acta biochimica et biophysica Sinica · 2026
    Review
  15. Review
  16. Article
  17. Review
  18. CD74Journal of translational medicine · 2025
    Article
  19. Review
  20. Review

15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Rosaely Casalegno GarduñoMucosal Immunology Group, Department of Pediatrics, Rostock University Medical Center, Rostock, Germany.
Jan DäbritzMucosal Immunology Group, Department of Pediatrics, Rostock University Medical Center, Rostock, Germany.
Queen Mary University of London · GBUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

CD8

Indexed as

Immunity, MucosalAnimalsCD8-Positive T-LymphocytesColitis, UlcerativeCrohn DiseaseCytotoxicity, ImmunologicHumansImmunologic MemoryImmunotherapyInflammation MediatorsInterleukin-17Intestinal MucosaLymphocyte ActivationPhenotypeInflammation MediatorsInterleukin-17CD8+ Tc1Crohn´s diseaseIBDTc17T regsTRMulcerative colitis

Identifiers

PMID34707610
PMCPMC8542854
OpenAlexW3205943342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.