Evidence map›Paper›PMID 34707599›Full record

ArticleFrontiers in immunology2021

Podoplanin Drives Motility of Active Macrophage

Yi Ying Cheok, Grace Min Yi Tan, Keith Conrad Fernandez, Yee Teng Chan, Chalystha Yie Qin Lee, Heng Choon Cheong, Chung Yeng Looi, Jamuna Vadivelu, Suhailah Abdullah, Won Fen Wong

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Distinctive transcriptomic and epigenomic signatures of bone marrow-derived myeloid cells and microglia in CNS autoimmunity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  2. Review
  3. Article
  4. Innate Immunity Crosstalk withInternational journal of molecular sciences · 2022
    Review
  5. Article
  6. Review
  7. An Overview ofMicroorganisms · 2021
    Review
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yi Ying CheokDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Grace Min Yi TanDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Keith Conrad FernandezDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Yee Teng ChanDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Chalystha Yie Qin LeeDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Heng Choon CheongDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Chung Yeng LooiSchool of Bioscience, Taylor's University, Subang Jaya, Selangor, Malaysia.
Jamuna VadiveluDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Suhailah AbdullahDepartment of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
Won Fen WongDepartment of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
University of Malaya · MYUniversity Malaya Medical Centre · MYTaylor's University · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Podoplanin (Pdpn) is a mucin-type transmembrane protein that has been implicated in multiple physiological settings including lymphangiogenesis, platelet aggregation, and cancer metastasis. Here, we reported an absence of Pdpn transcript expression in the resting mouse monocytic macrophages, RAW264.7 cells; intriguingly, a substantial upregulation of Pdpn was observed in activated macrophages following

Indexed as

AnimalsCell MovementFilaminsHelicobacter InfectionsHelicobacter pyloriHumansMacrophagesMembrane GlycoproteinsMicePodoplaninRAW 264.7 CellsTHP-1 CellsFilaminsMembrane GlycoproteinsPDPN protein, humanPdpn protein, mousePodoplanincell migrationFilamin CHelicobacter pyloriinterleukin-1βmacrophagepodoplanin

Identifiers

PMID34707599
PMCPMC8543000
OpenAlexW3207629783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.