Evidence map›Paper›PMID 34707576›Full record

ArticleFrontiers in microbiology2021

Evaluating the Cost of Pharmaceutical Purification for a Long-Duration Space Exploration Medical Foundry.

Matthew J McNulty, Aaron J Berliner, Patrick G Negulescu, Liber McKee, Olivia Hart, Kevin Yates, Adam P Arkin, Somen Nandi, Karen A McDonald

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Matthew J McNultyCenter for the Utilization of Biological Engineering in Space (CUBES), Berkeley, CA, United States.
Aaron J BerlinerCenter for the Utilization of Biological Engineering in Space (CUBES), Berkeley, CA, United States.
Patrick G NegulescuCenter for the Utilization of Biological Engineering in Space (CUBES), Berkeley, CA, United States.
Liber McKeeDepartment of Chemical Engineering, University of California, Davis, Davis, CA, United States.
Olivia HartDepartment of Chemical Engineering, University of California, Davis, Davis, CA, United States.
Kevin YatesCenter for the Utilization of Biological Engineering in Space (CUBES), Berkeley, CA, United States.
Adam P ArkinCenter for the Utilization of Biological Engineering in Space (CUBES), Berkeley, CA, United States.
Somen NandiCenter for the Utilization of Biological Engineering in Space (CUBES), Berkeley, CA, United States.
Karen A McDonaldCenter for the Utilization of Biological Engineering in Space (CUBES), Berkeley, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are medical treatment vulnerabilities in longer-duration space missions present in the current International Space Station crew health care system with risks, arising from spaceflight-accelerated pharmaceutical degradation and resupply lag times. Bioregenerative life support systems may be a way to close this risk gap by leveraging

Indexed as

equivalent system masshuman exploration missionin situ resource utilizationmonoclonal antibody purificationpharmaceutical foundryspace exploration medical foundryspace systems bioengineeringtechno-economic analysis

Identifiers

PMID34707576
PMCPMC8542935

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.