ArticleFrontiers in endocrinology2021
The Association Between Triglyceride-Glucose Index as a Marker of Insulin Resistance and the Risk of Breast Cancer.
Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- The Associations Between the TyG Index and the Risk of Cancer-A Systematic Review and Meta-Analysis.Cancer medicine · 2025Pooled it
- Association Between Triglyceride-Glucose Index and Breast Cancer: A Systematic Review and Meta-Analysis.Cancer reports (Hoboken, N.J.) · 2025Pooled it
- Association between triglyceride glucose index and risk of cancer: A meta-analysis.Frontiers in endocrinology · 2022Pooled it
- Association Between Triglyceride-Glucose Index and Risk of Cancer: A Systematic Review and Meta-Analysis.Journal of personalized medicine · 2026Review
- Machine learning-based association analysis of triglyceride-glucose index with melanoma prevalence and all-cause mortality: insights from cross-sectional NHANES 1999-2018 data and an external hospital-based dataset.Frontiers in nutrition · 2026Article
- The correlation between the triglyceride-glucose index and the odds of cervical cancer.Frontiers in oncology · 2026Article
- Correlation between TyG index and its modified index with breast cancer risk in women a study based on NHANES database and real-world data.Frontiers in oncology · 2026Article
- Triglyceride glucose related indices predict incident breast cancer risk in a population based cohort study.Discover oncology · 2025Article
- Association between triglyceride-glucose index and thyroid nodule: a cross-sectional study in Western Liaoning Province, China.Scientific reports · 2025Article
- Association between triglyceride-glucose related indicators, genetic risk, and incident breast cancer among postmenopausal women in UK Biobank.BMC cancer · 2025Article
- Association between triglyceride‑glucose index as a marker of insulin resistance and the risk of malignant melanoma: A retrospective study.Oncology letters · 2025Article
- Evaluating lipid-driven insulin resistance via TyG index in breast cancer patients: Toward effective secondary prevention.German medical science : GMS e-journal · 2025Article
- The atherogenic index of plasma and triglyceride-glucose index as promising predictors of overall and disease-free survival in postoperative breast cancer patients.Frontiers in endocrinology · 2025Article
- Article
- Higher peripheral blood mitochondrial DNA copy number and relative telomere length in under 48 years Indonesian breast cancer patients.BMC research notes · 2024Article
- Triglyceride-glucose index is a risk factor for breast cancer in China: a cross-sectional study.Lipids in health and disease · 2024Article
- Genetically Proxied Therapeutic Effect of Lipid-Lowering Drugs Use, Breast Cancer, and Endometrial Cancer's Risk: A Drug Target-Based Mendelian Randomization Study.International journal of women's health · 2024Article
- Correlation between fasting blood glucose level and risk of breast cancer in women: a single-center, prospective cohort study.Frontiers in oncology · 2024Article
- Association between triglyceride glucose index and breast cancer in 142,184 Chinese adults: findings from the REACTION study.Frontiers in endocrinology · 2024Article
- Triglyceride-glucose index is a predictor of the risk of prostate cancer: a retrospective study based on a transprostatic aspiration biopsy population.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
19 authors at 7 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: This study aims to evaluate the association and dose-response between triglyceride-glucose (TyG) index and breast cancer. Method: This is a multicenter case-control study conducted in six public referral hospitals in Indonesia. Cases are individuals aged 19 years or above who were diagnosed with breast cancer within 1 year of diagnosis, based on histopathology and immunohistochemistry. Controls were recruited from corresponding hospitals. TyG index was determined by the formula: ln (fasting TG [mg/dl] × fasting glucose [mg/dl]). Results: There were 212 participants in the breast cancer group and 212 participants in the control group. TyG index was higher in patients with breast cancer (median 8.65 [7.38, 10.9] vs. 8.30 [7.09, 10.84], Conclusion: TyG index was associated with breast cancer in a nonlinear dose-response fashion.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.