Evidence map›Paper›PMID 34707568›Full record

ArticleFrontiers in endocrinology2021

Case Report: Medullary Thyroid Cancer Workup Initiated by Unexpectedly High Procalcitonin Level-Endocrine Training Saves Life in the COVID-19 Unit.

Livia Sira, Zoltán Balogh, Eszter Vitális, Dávid Kovács, Ferenc Győry, Csaba Molnár, Miklos Bodor, Endre V Nagy

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Livia SiraDivision of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Zoltán BaloghDivision of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Eszter VitálisDivision of Infectious Diseases, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Dávid KovácsDepartment of Surgery, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Ferenc GyőryDepartment of Surgery, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Csaba MolnárDepartment of Pathology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Miklos BodorDivision of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
Endre V NagyDivision of Endocrinology, Department of Medicine, Faculty of Medicine, University of Debrecen, Debrecen, Hungary.
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that has caused a worldwide pandemic. The majority of medullary thyroid cancers present as a thyroid nodule. At the time of diagnosis, cervical lymph nodes and distant metastases are frequently detected. Case Report: Here, we present a case of a 46-year-old man with coronavirus disease (COVID) pneumonia, who had persistently high serum procalcitonin levels despite normal C-reactive protein levels. The attending infectologist happened to be a colleague who spent some time, as part of her internal medicine rotation, in the Endocrine Ward and recalled that medullary thyroid cancer might be the cause. This led to the timely workup and treatment of the medullary cancer.

Indexed as

Biomarkers, TumorCarcinoma, NeuroendocrineCOVID-19C-Reactive ProteinEndocrinologyHumansIncidental FindingsLymph NodesMaleMiddle AgedProcalcitoninSARS-CoV-2Thyroid NeoplasmsThyroid NoduleBiomarkers, TumorC-Reactive ProteinProcalcitonincalcitoninendocrine rotationmedullary thyroid cancerprocalcitoninsevere acute respiratory syndrome coronavirus 2

Identifiers

PMID34707568
PMCPMC8543013
OpenAlexW3207136124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.