Evidence map›Paper›PMID 34707559›Full record

ArticleFrontiers in neurology2021

Altered Degree Centrality of Brain Networks in Parkinson's Disease With Freezing of Gait: A Resting-State Functional MRI Study.

Chaoyang Jin, Shouliang Qi, Yueyang Teng, Chen Li, Yudong Yao, Xiuhang Ruan, Xinhua Wei

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Topography of Regional Cerebral GABAThe European journal of neuroscience · 2026
    Article
  2. Article
  3. Effects of levodopa on motor and cerebellar network connectivity in Parkinson's disease.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Article
  4. Article
  5. Cholinergic basal forebrain atrophy in Parkinson's disease with freezing of gait.Annals of clinical and translational neurology · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Chaoyang JinCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.
Shouliang QiCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.
Yueyang TengCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.
Chen LiCollege of Medicine and Biological Information Engineering, Northeastern University, Shenyang, China.
Yudong YaoDepartment of Electrical and Computer Engineering, Stevens Institute of Technology, Hoboken, NJ, United States.
Xiuhang RuanDepartment of Radiology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Xinhua WeiDepartment of Radiology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Northeastern University · CNGuangzhou First People's Hospital · CNSouth China University of Technology · CNStevens Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Freezing of gait (FOG) in Parkinson's disease (PD) leads to devastating consequences; however, little is known about its functional brain network. We explored the differences in degree centrality (DC) of functional networks among PD with FOG (PD FOG+), PD without FOG (PD FOG-), and healthy control (HC) groups. In all, 24 PD FOG+, 37 PD FOG-, and 22 HCs were recruited and their resting-state functional magnetic imaging images were acquired. The whole brain network was analyzed using graph theory analysis. DC was compared among groups using the two-sample

Indexed as

degree centralityfreezing of gaitfunctional brain networkParkinson's diseaseresting-state fMRI

Identifiers

PMID34707559
PMCPMC8542685
OpenAlexW3205444579

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.