Evidence map›Paper›PMID 34707352›Full record

ArticleClinical interventions in aging2021

How a Patient Personalised Clinical Pharmacy Programme Can Secure Therapeutic Care in an Orthogeriatric Care Pathway (5P Project)?

Marine Barral, Julie Martin, Emmanuelle Carre, Audrey Janoly-Dumenil, Florence Ranchon, Stéphanie Parat, Catherine Rioufol, Sylvain Goutelle, Laurent Bourguignon, Teddy Novais and 8 more

Abstract read
In one paragraph

Article in Clinical interventions in aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Marine Barral *Pharmacie, Hospices Civils de Lyon, Lyon, France.
Julie Martin *Pharmacie, Hospices Civils de Lyon, Lyon, France.
Emmanuelle CarrePharmacie Hôpital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Audrey Janoly-DumenilPharmacie Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Florence RanchonPharmacie Hôpital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Stéphanie ParatPharmacie Hôpital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Catherine RioufolPharmacie Hôpital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Sylvain GoutelleInstitut des Sciences Pharmaceutiques et Biologiques, Univ Claude Bernard Lyon 1, Univ Lyon 1, Lyon, France.
Laurent BourguignonInstitut des Sciences Pharmaceutiques et Biologiques, Univ Claude Bernard Lyon 1, Univ Lyon 1, Lyon, France.
Teddy NovaisInstitut des Sciences Pharmaceutiques et Biologiques, Univ Claude Bernard Lyon 1, Univ Lyon 1, Lyon, France.
Sebastien DohService de Gériatrie Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Matthieu MalatrayService de Chirurgie Orthopédique Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Philippe ChaudierService de Chirurgie Orthopédique Hôpital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Jerome GauthierService d'anesthésie et réanimation Hôpital Lyon Sud, Hospices Civils de Lyon, Pierre-Bénite, France.
Christine PivotPharmacie Hôpital Edouard Herriot, Hospices Civils de Lyon, Lyon, France.
Christelle MouchouxInstitut des Sciences Pharmaceutiques et Biologiques, Univ Claude Bernard Lyon 1, Univ Lyon 1, Lyon, France.
Delphine HoegyPharmacie, Hospices Civils de Lyon, Lyon, France.ORCID 0000-0002-8659-6073
5P Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA new model was developed for integrating a personalised clinical pharmacy programme (5P project) into the orthogeriatric care pathway.

objectiveTo secure the therapeutic care of orthogeriatric patients. DESIGN AND

settingProspective descriptive study in a multisite teaching hospital from June 2019 to January 2020. SUBJECTS: Patients aged ≥75 years admitted for hip fracture.

methodsA prescription review was performed for all patients at inclusion. Other clinical pharmacy activities (additional prescription review, pharmaceutical interviews, medication reconciliation) were dedicated to "high-risk" patients. Potential medication errors (ME), either pharmaceutical interventions (PI) or unintentional discrepancies (UID), were recorded. The potential clinical impact of PI was evaluated by a pluriprofessional expert panel using a validated tool.

resultsIn the 455 patients included, 955 potential ME were detected, that is ≥1 potential ME for 324/455 (71%) patients. In acute care, 561 PI were formulated during prescription review for 440/455 (97%) patients and 348/561 (62%) were accepted by physicians. Medication reconciliation was performed for 213 patients, 316 UID were identified. In rehabilitation units, a second prescription review was performed for 112/122 (92%) "high-risk" patients, leading to 61 PI. The clinical impact was evaluated for 519/622 (83%) PI. A consensus was obtained for 310/519 (60%) PI: 147/310 (47%) were rated as having minor clinical impact, 138/310 (45%) moderate, 22/310 (7%) major, 2/310 (0.6%) vital, and 1/310 (0.3%) null.

conclusionThe 5P project secured the orthogeriatric care pathway by detecting a great number of potential ME, including PI mostly considered as having a significant clinical impact.

Indexed as

PharmacyPharmacy Service, HospitalHumansMedication ErrorsMedication ReconciliationProspective Studiesclinical relevancefrail elderlyhip fracturemedication errorspharmaceutical services

Identifiers

PMID34707352
PMCPMC8544550

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.