Evidence map›Paper›PMID 34707258›Full record

ReviewNature reviews. Gastroenterology & hepatology2022

Advancing the global public health agenda for NAFLD: a consensus statement.

Jeffrey V Lazarus, Henry E Mark, Quentin M Anstee, Juan Pablo Arab, Rachel L Batterham, Laurent Castera, Helena Cortez-Pinto, Javier Crespo, Kenneth Cusi, M Ashworth Dirac and 24 more

Abstract readReviewConsensus Statement
PubMed Publisher
In one paragraph

Review in Nature reviews. Gastroenterology & hepatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 386 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
386citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

386 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Guideline
  6. Article
  7. Article
  8. Article
  9. Review
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  12. Review
  13. Gene-Based Clustering Identifies QSOX1 and IL1RAP as Biomarkers of Metabolic Dysfunction-Associated Steatotic Liver Disease.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  14. Article
  15. Review
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  18. Review
  19. Review
  20. Article

326 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Jeffrey V LazarusBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Barcelona, Spain. Jeffrey.Lazarus@isglobal.org.ORCID http://orcid.org/0000-0001-9618-2299
Henry E MarkEASL International Liver Foundation, Geneva, Switzerland.ORCID http://orcid.org/0000-0002-8022-4279
Quentin M AnsteeTranslational & Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID http://orcid.org/0000-0002-9518-0088
Juan Pablo ArabDepartamento de Gastroenterologia, Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile.ORCID http://orcid.org/0000-0002-8561-396X
Rachel L BatterhamCentre for Obesity Research, University College London and National Institute of Health Research, UCLH Biomedical Research Centre, London, UK.
Laurent CasteraDepartment of Hepatology, Hôpital Beaujon, Université de Paris, Paris, France.ORCID http://orcid.org/0000-0002-6715-8588
Helena Cortez-PintoClínica Universitária de Gastrenterologia, Laboratório de Nutrição, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal.ORCID http://orcid.org/0000-0002-8537-8744
Javier CrespoGastroenterology and Heptology Unit, Hospital Universitario Marqués de Valdecilla, Santander, IDIVAL, Santander, Spain.ORCID http://orcid.org/0000-0001-8248-0172
Kenneth CusiDivision of Endocrinology, Diabetes & Metabolism, Department of Medicine, Veterans Health Administration and University of Florida, Gainesville, FL, USA.
M Ashworth DiracDepartment of Health Metrics Sciences, Department of Family Medicine, University of Washington, Seattle, WA, USA.
Sven FrancqueDepartment of Gastroenterology Hepatology, University Hospital Antwerp, Antwerp, Belgium.ORCID http://orcid.org/0000-0002-7527-4714
Jacob GeorgeStorr Liver Centre, Westmead Institute for Medical Research, Westmead Hospital and University of Sydney, Sydney, New South Wales, Australia.ORCID http://orcid.org/0000-0002-8421-5476
Hannes HagströmDepartment of Medicine, Karolinska Institutet, Stockholm, Sweden.
Terry T-K HuangCenter for Systems and Community Design and NYU-CUNY Prevention Research Center, Graduate School of Public Health and Health Policy, City University of New York, New York, NY, USA.ORCID http://orcid.org/0000-0001-5544-5187
Mona H IsmailDivision of Gastroenterology, Department of Internal Medicine, King Fahd Hospital of the University, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.ORCID http://orcid.org/0000-0001-6371-3997
Achim KautzKautz5, Köln, Germany.
Shiv Kumar SarinDepartment of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.ORCID http://orcid.org/0000-0002-0544-5610
Rohit LoombaDepartment of Medicine, NAFLD Research Center, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-4845-9991
Veronica MillerUniversity of California Berkeley, School of Public Health, Forum for Collaborative Research, Washington, DC, USA.
Philip N NewsomeNational Institute for Health Research Birmingham Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham, Birmingham, UK.
Michael NinburgHepatitis Education Project, Seattle, WA, USA.ORCID http://orcid.org/0000-0001-8592-5878
Ponsiano OcamaDepartment of Medicine, College of Health Sciences, Makerere University, Kampala, Uganda.
Vlad RatziuAssistance Publique-Hôpitaux de Paris, Hôpital Pitie-Salpetriere, University of Paris, Paris, France.
Mary RinellaDepartment of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.
Diana RomeroDepartment of Community Health and Social Sciences, CUNY Graduate School of Public Health and Health Policy, New York, NY, USA.ORCID http://orcid.org/0000-0002-4832-9564
Manuel Romero-GómezUCM Digestive Diseases, CIBEREHD and IBIS, Virgen del Rocío University Hospital, University of Seville, Seville, Spain.ORCID http://orcid.org/0000-0001-8494-8947
Jörn M SchattenbergMetabolic Liver Research Program, I. Department of Medicine, University Medical Centre Mainz, Mainz, Germany.ORCID http://orcid.org/0000-0002-4224-4703
Emmanuel A TsochatzisUniversity College London Institute for Liver and Digestive Health, Royal Free Hospital, London, UK.
Luca ValentiDepartment of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy.
Vincent Wai-Sun WongDepartment of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China.ORCID http://orcid.org/0000-0003-2215-9410
Yusuf YilmazDepartment of Gastroenterology, Marmara University School of Medicine, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-4518-5283
Zobair M YounossiCenter for Liver Diseases, Inova Medicine, Falls Church, VA, USA.
Shira Zelber-SagiUniversity of Haifa, Faculty of Social Welfare and Health Sciences, School of Public Health, Mount Carmel, Haifa, Israel.
NAFLD Consensus Consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects approximately one-quarter of the global adult population, causing a substantial burden of ill health with wide-ranging social and economic implications. It is a multisystem disease and is considered the hepatic component of metabolic syndrome. Unlike other highly prevalent conditions, NAFLD has received little attention from the global public health community. Health system and public health responses to NAFLD have been weak and fragmented, and, despite its pervasiveness, NAFLD is largely unknown outside hepatology and gastroenterology. There is only a nascent global public health movement addressing NAFLD, and the disease is absent from nearly all national and international strategies and policies for non-communicable diseases, including obesity. In this global Delphi study, a multidisciplinary group of experts developed consensus statements and recommendations, which a larger group of collaborators reviewed over three rounds until consensus was achieved. The resulting consensus statements and recommendations address a broad range of topics - from epidemiology, awareness, care and treatment to public health policies and leadership - that have general relevance for policy-makers, health-care practitioners, civil society groups, research institutions and affected populations. These recommendations should provide a strong foundation for a comprehensive public health response to NAFLD.

Indexed as

HumansNon-alcoholic Fatty Liver Disease

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.