ArticleScientific reports2021
Immediate application of negative pressure wound therapy following lower extremity flap reconstruction in sixteen patients.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed, 12 citations in OpenAlex.
- The efficacy and safety of different negative-pressure wound therapy gradients on flaps outcomes.Updates in surgery · 2025Trial
- Reverse Sural Flap for Reconstruction of a Distal Leg Soft-Tissue Defect Following Dog Bite Injury: A Case Report.Cureus · 2026Article
- Mythbusters in Microsurgery: Evaluating Evidence and Debunking Dogma-A Practical Review: Part I.Plastic and reconstructive surgery. Global open · 2026Review
- Vacuum-assisted closure of the scalp flap following malignant cerebral edema during craniotomy: pediatric case presentations and review of the literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Review
- Utilizing Low-cost Vacuum-assisted Closure as Adjuvant Therapy in Soft Tissue Reconstruction for a Mangled Upper Extremity.Plastic and reconstructive surgery. Global open · 2024Article
- Roles of negative pressure wound therapy for scar revision.Frontiers in physiology · 2023Review
- Flap monitoring with incisional negative pressure wound therapy (NPWT) in diabetic foot patients.Scientific reports · 2022Article
- Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Negative pressure wound therapy (NPWT) is usually applied in wound management and soft-tissue salvage after the development of complications. However, immediate postoperative application of NPWT over the flap coverage is seldom reported. We evaluate the effectiveness of immediate postoperative application of NPWT following fasciocutaneous or muscle flap coverage for lower leg reconstruction. A retrospective review of patients who underwent either fasciocutaneous or muscle flap coverage of lower leg soft-tissue defects applied with NPWT immediately after surgery was conducted in a level I trauma center. Sixteen patients, with an average age of 51.2 years, were included in the study. Nine patients had trauma-related soft-tissue loss, six had subsequent soft-tissue defects after debridement, and one had burn injury. Two patients had been treated with free anterolateral thigh flaps, 11 with pedicle flaps, and three with muscle flaps. All flaps survived except for those in two patients with venous congestion on postoperative day 1, which needed further debridement and skin grafting. Therefore, the use of immediate incisional NPWT is an alternative for wound care following flap coverage. The U-shaped design allows easy flap observation and temperature check. Furthermore, this method eliminates any concerns of vascular pedicle compression under negative pressure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.