Evidence map›Paper›PMID 34706704›Full record

ArticleBMC oral health2021

Detection of xerostomia, Sicca, and Sjogren's syndromes in a national sample of adults.

Indre Stankeviciene, Alina Puriene, Diana Mieliauskaite, Lina Stangvaltaite-Mouhat, Jolanta Aleksejuniene

Open access · goldAbstract read
In one paragraph

Article in BMC oral health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Molecular Insights into Oral Manifestations in Sjögren's Disease.International journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
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  15. Oral Health among Adult Residents in Vilnius, Lithuania.International journal of environmental research and public health · 2022
    Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Indre StankevicieneInstitute of Dentistry, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Alina PurieneInstitute of Dentistry, Faculty of Medicine, Vilnius University, Vilnius, Lithuania.
Diana MieliauskaiteDepartment of Experimental, Preventive and Clinical Medicine, State Research Institute Centre for Innovative Medicine, Vilnius, Lithuania.
Lina Stangvaltaite-MouhatOral Health Centre of Expertise in Eastern Norway, Oslo, Norway. lina.stangvaltaite@uit.no.
Jolanta AleksejunieneDepartment of Oral Health Sciences, Faculty of Dentistry, University of British Columbia, Vancouver, Canada.
Vilnius University · LTState Research Institute Centre for Innovative Medicine · LTUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the prevalence and determinants of xerostomia among adults and identify how many of the ones experiencing xerostomia have Sicca and Sjogren's syndromes. MATERIALS AND

methodsThis cross-sectional study included 1405 35-74-year-old Lithuanians (51.7% response rate) from the five largest Lithuanian cities and 10 peri-urban and rural areas that were randomly selected from each of the 10 Lithuanian counties. Xerostomia was determined by the self-reported experience of dry mouth as "often" or "always". A dentist diagnosed Sicca syndrome by unstimulated whole sialometry and the Schirmer's test, and all cases were referred to a rheumatologist to confirm Sjogren's syndrome. Self-reported questionnaires collected data about the determinants.

resultsThe prevalence of xerostomia was 8.0% (n = 112), Sicca syndrome was diagnosed for 8 participants (0.60%), and Sjogren's syndrome for 2 participants (0.14%), with this being the first time it was diagnosed. Experiencing xerostomia was associated with older age (OR 1.7, 95% CI 1.1-2.6), urban residence (OR 3.3, 95% CI 1.6-5.0), presence of systemic diseases (OR 2.5, 95% CI 1.4-3.3), and the use of alcohol (OR 0.6, 95% CI 0.4-0.9). The higher proportion of participants with Sicca syndrome involved females, of older age, having systemic diseases, and using medications.

conclusionsThe prevalence of xerostomia was 8.0% and the determinants of xerostomia were older age, urban residence, systemic diseases, and absence of using alcohol. In total, 0.6% of participants had Sicca syndrome, which was more prevalent among females, older subjects, those with systematic diseases, and those using medications. Sjogren's syndrome was diagnosed in 0.14% of participants. Clinical relevance Dental clinicians need to be trained to identify potential Sjogren's syndrome cases.

Indexed as

Sjogren's SyndromeXerostomiaAdultAgedCross-Sectional StudiesFemaleHumansSelf ReportSurveys and QuestionnairesAdultsSalivaSicca syndromeSjogren's syndromeXerostomia

Identifiers

PMID34706704
PMCPMC8555192
OpenAlexW3207993717

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.