Evidence map›Paper›PMID 34706697›Full record

ArticleBMC cancer2021

Prognostic value of metabolic activity of the psoas muscle evaluated by preoperative

Keunyoung Kim, In-Joo Kim, Kyoungjune Pak, Taewoo Kang, Young Mi Seol, Young Jin Choi, Hyojeong Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Keunyoung KimDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.
In-Joo KimDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.
Kyoungjune PakDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.
Taewoo KangDepartment of Surgery, Busan Cancer Center, Pusan National University Hospital and Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea.
Young Mi SeolDepartment of Hematology-Oncology, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan, 49241, South Korea.
Young Jin ChoiDepartment of Hematology-Oncology, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan, 49241, South Korea.
Hyojeong KimDepartment of Hematology-Oncology, Pusan National University School of Medicine and Biomedical Research Institute, Pusan National University Hospital, 179 Gudeok-ro, Seo-gu, Busan, 49241, South Korea. leonkim80@pusan.ac.kr.
Pusan National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study aimed to evaluate the potential of metabolic activity of the psoas muscle measured by

methodsThe medical records of 288 patients who had undergone surgical resection for stages I-III invasive ductal carcinoma of the breast between January 2014 and December 2014 in Pusan National University Hospital were reviewed. The standardized uptake values (SUVs) of the bilateral psoas muscle were normalized using the mean SUV of the liver. SUVRmax was calculated as the ratio of the maximum SUV of the average bilateral psoas muscle to the mean SUV of the liver. SUVRmean was calculated as the ratio of the mean SUV of the bilateral psoas muscle to the mean SUV of the liver.

resultsUnivariate analyses identified a higher T stage, higher N stage, estrogen receptor negativity, progesterone receptor negativity, human epidermal growth factor receptor 2 positivity, triple-negative breast cancer, mastectomy (rather than breast-conserving surgery), SUVRmean > 0.464, and SUVRmax > 0.565 as significant adverse factors for disease-free survival (DFS). Multivariate Cox regression analysis revealed that N3 stage (hazard ratio [HR] = 5.347, P = 0.031) was an independent factor for recurrence. An SUVRmax > 0.565 (HR = 4.987, P = 0.050) seemed to have a correlation with shorter DFS.

conclusionsA higher SUVRmax of the psoas muscle, which could be a surrogate marker of insulin resistance, showed strong potential as an independent prognostic factor for recurrence in patients with resectable breast cancer.

Indexed as

Insulin ResistancePositron Emission Tomography Computed TomographyAdultAgedBreast NeoplasmsCarcinoma, Ductal, BreastCross-Sectional StudiesFemaleFluorodeoxyglucose F18HumansLiverMastectomyMiddle AgedNeoplasm Recurrence, LocalPreoperative CarePrognosisFluorodeoxyglucose F18RadiopharmaceuticalsBreast neoplasmsInsulin resistancePositron emission tomography-computed tomographyTreatment outcomes

Identifiers

PMID34706697
PMCPMC8555075
OpenAlexW3169926313

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.