ArticleBMC psychiatry2021
Prospective association between depressive symptoms and stroke risk among middle-aged and older Chinese.
Article in BMC psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Association between psychiatric disorders and the risk of stroke: a meta-analysis of cohort studies.Frontiers in neurology · 2024Pooled it
- Association Between Depressive Symptoms and Incidence of Stroke in a Population With Cardiovascular-Kidney-Metabolic Syndrome Stages 0 to 3: Nationwide Prospective Cohort Study.Interactive journal of medical research · 2026Article
- The non-linear association between depression scores and all-cause mortality: a cohort study based on NHANES 2005-2018 data.Scientific reports · 2025Article
- The dual impact of physical exercise on depression and fall risk in older Chinese adults - evidence from CHARLS 2020.Frontiers in public health · 2025Article
- Comparison of Risk of Stroke in Patients With and Without Depression: A Systematic Review and Meta-Analysis.Cureus · 2024Review
- Depression, anxiety, insomnia, stress, and the way of coping emotions as risk factors for ischemic stroke and their influence on stroke severity: A case-control study in Lebanon.Frontiers in psychiatry · 2023Article
- Association between changes in depressive symptoms and hip fracture among middle-aged and older Chinese individuals: a prospective cohort study.BMC geriatrics · 2022Article
- Prospective association between depressive symptoms and hip fracture and fall among middle-aged and older Chinese individuals.BMC psychiatry · 2022Article
- Depressive symptoms increase the risk of falls and injurious falls in Chinese adults aged ≥ 45 years: A 3-year cohort study.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThis study aimed to assess the association between baseline symptoms and changes in depressive symptoms and stroke incidents.
methodsWe used data from the Chinese Health and Retirement Longitudinal Study conducted in 2013, 2015, and 2018. In total, 10,100 individuals aged ≥45 years and without a history of stroke in 2013 were included. Depressive symptoms were measured using the 10-item version of the Center for Epidemiological Studied Depression scale (elevated depressive symptoms cutoff ≥10). Changes of depressive symptoms were assessed by two successive surveys (stable low/no, recent onset, recently remitted, and stable high depressive symptoms). We assessed whether baseline depressive symptoms and changes of them were associated with stroke incidents reported through 2018. Logistic regression analyses adjusted for age, gender, education, marital status and other potential confounders were performed.
resultsFor the analysis of baseline depressive symptoms and stroke (n = 10,100), 545 (5.4%) reported stroke incidents in the following 5-year period. Individuals with elevated depressive symptoms in 2013 experienced a markedly higher stroke risk (odds ratio (OR) = 1.53, 95% confidence interval (CI) = 1.28-1.84) compared with those without elevated depressive symptoms. In the analysis of changes in depressive symptoms (n = 8491, 430 (5.1%) stroke events), participants with stable high (OR = 2.01, 95% CI = 1.58-2.56) and recent-onset (OR = 1.39, 95% CI = 1.04-1.85) depressive symptoms presented higher stroke risk compared to those with stable low/no depressive symptoms, while recently remitted symptoms (OR = 1.12, 95% CI = 0.80-1.57) were not associated with stroke risk.
conclusionsIn conclusion, stable high and newly started depressive symptoms were associated with increased stroke risk, whereas the improvement of depressive symptoms was not related to increase in stroke risk, suggesting that stroke risk may be decreased by effective management of depressive symptoms.
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