Evidence map›Paper›PMID 34706130›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2022

Laparoscopic versus open surgery for left flexure colon cancer: A propensity score matched analysis from an international cohort.

Corrado Pedrazzani, Giulia Turri, Soo Yeun Park, Koya Hida, Yudai Fukui, Jacopo Crippa, Giovanni Ferrari, Matteo Origi, Gaya Spolverato, Matteo Zuin and 10 more

Open access · bronzeAbstract read
In one paragraph

Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Short- and long-term results of openWorld journal of gastrointestinal surgery · 2023
    Article
  6. Laparoscopic versus open surgery for left flexure colon cancer: A propensity score matched analysis from an international cohort.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 5 countries.

Corrado PedrazzaniDivision of General and Hepatobiliary Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.ORCID 0000-0003-2431-6117
Giulia TurriDivision of General and Hepatobiliary Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.ORCID 0000-0001-6150-6812
Soo Yeun ParkColorectal Cancer Centre, Kyungpook National University Medical Centre, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID 0000-0003-4821-2101
Koya HidaDepartment of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0001-7210-7075
Yudai FukuiDepartment of Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.ORCID 0000-0002-7262-7975
Jacopo CrippaDivision of Colon and Rectal Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA.ORCID 0000-0003-4090-0989
Giovanni FerrariDepartment of General Surgery, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.ORCID 0000-0002-5405-9046
Matteo OrigiDepartment of General Surgery, Niguarda Hospital, ASST Grande Ospedale Metropolitano Niguarda, Milan, Italy.ORCID 0000-0003-4191-3378
Gaya SpolveratoFirst Surgical Clinic Section, Department of Surgery, Oncology, and Gastroenterology, University of Padova, Padova, Italy.ORCID 0000-0002-7275-2573
Matteo ZuinFirst Surgical Clinic Section, Department of Surgery, Oncology, and Gastroenterology, University of Padova, Padova, Italy.ORCID 0000-0002-3571-0120
Sung Uk BaeDivision of Colorectal Surgery, Department of Surgery, School of Medicine, Keimyung University and Dongsan Medical Centre, Daegu, Korea.ORCID 0000-0002-7876-4196
Seong Kyu BaekDivision of Colorectal Surgery, Department of Surgery, School of Medicine, Keimyung University and Dongsan Medical Centre, Daegu, Korea.ORCID 0000-0001-6427-8675
Andrea CostanziGeneral Surgery 3, ASST-Monza, Desio Hospital, Desio, Italy.
Dario MaggioniGeneral Surgery 3, ASST-Monza, Desio Hospital, Desio, Italy.
Gyung Mo SonDepartment of Surgery, Pusan National University Yangsan Hospital, School of Medicine, Pusan National University, Yangsan, Korea.ORCID 0000-0002-8861-6293
Andrea ScalaDepartment of Colorectal and Minimal Access Surgery, Royal Surrey NHS Foundation Trust, Guildford, UK.
Timothy RockallDepartment of Colorectal and Minimal Access Surgery, Royal Surrey NHS Foundation Trust, Guildford, UK.ORCID 0000-0001-8488-7005
David W LarsonDivision of Colon and Rectal Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota, USA.
Alfredo GuglielmiDivision of General and Hepatobiliary Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.ORCID 0000-0003-1713-4307
Gyu Seog ChoiColorectal Cancer Centre, Kyungpook National University Medical Centre, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID 0000-0001-5476-4610
University of Verona · ITAzienda Ospedaliera San Gerardo · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITKeimyung University Dongsan Medical Center · KRKyoto University · JPKyungpook National University Medical Center · KRMayo Clinic · USRoyal Surrey NHS Foundation Trust · GBUniversity of Padua · ITPusan National University Yangsan Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimSurgical treatment of splenic flexure cancer (SFC) still presents some debated issues, including the role of laparoscopic surgery. The literature is based on small single-centre series, while randomized controlled studies comparing open and laparoscopic treatment for colon cancer exclude SFC. This study aimed to determine the role of laparoscopic surgery in the treatment of SFC, comparing short- and long-term outcomes with open surgery.

methodThis was an international multicentre retrospective cohort study that analysed patients from 10 tertiary referral centres. From a cohort of 641 cases, 484 patients with Stage I-III SFC submitted to elective surgery with curative intent were selected. After 1:1 propensity score matching, 130 patients in the laparoscopic group (LapGroup) were compared with 130 patients in the open surgery group (OpenGroup).

resultsAfter propensity score matching, the two groups were comparable for demographic and clinical parameters. OpenGroup presented a higher incidence of overall (P = 0.02) and surgery-related complications (P = 0.05) but a similar rate of severe complications (P = 0.75). Length of stay was notably shorter in the LapGroup (P = 0.001). Overall (P = 0.793) as well as cancer-specific survival (P = 0.63) did not differ between the two groups.

conclusionsElective laparoscopic surgery for Stage I-III SFC is feasible and associated with improved short-term postoperative outcomes compared to open surgery. Moreover, laparoscopic surgery appears to provide excellent long-term cancer outcomes.

Indexed as

Colonic NeoplasmsLaparoscopyCohort StudiesColectomyHumansPostoperative ComplicationsPropensity ScoreRetrospective StudiesTreatment Outcomecolon cancerlaparoscopyleft flexureprognosissplenic flexure

Identifiers

PMID34706130
PMCPMC9299165
OpenAlexW3210247040

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.