Evidence map›Paper›PMID 34705601›Full record

ReviewTranscription2021

Rho-dependent transcription termination: a revisionist view.

Zhitai Hao, Vladimir Svetlov, Evgeny Nudler

Abstract readReview
In one paragraph

Review in Transcription, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Article
  2. ARNA (New York, N.Y.) · 2026
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Co-transcriptional gene regulation in eukaryotes and prokaryotes.Nature reviews. Molecular cell biology · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Advancing evolution: Bacteria break down gene silencer to express horizontally acquired genes.BioEssays : news and reviews in molecular, cellular and developmental biology · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zhitai HaoDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.
Vladimir SvetlovDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.
Evgeny NudlerDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY, USA.

Funding

Transcription termination and gene regulation by Rho: Integrative analysisR01GM126891 · NIGMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NUDLER, EVGENY A · 2018 to 2021
$2.3M
Howard Hughes Medical InstituteNIGMS NIH HHS R01 GM126891
6 · The paper itself

Abstract

Rho is a hexameric bacterial RNA helicase, which became a paradigm of factor-dependent transcription termination. The broadly accepted ("textbook") model posits a series of steps, wherein Rho first binds C-rich

Indexed as

Escherichia coli ProteinsRho FactorDNA-Directed RNA PolymerasesEscherichia coliPeptide Elongation FactorsRNA, BacterialTranscriptional Elongation FactorsTranscription FactorsTranscription, GeneticDNA-Directed RNA PolymerasesEscherichia coli ProteinsnusA protein, E coliNusG protein, E coliPeptide Elongation FactorsRho FactorRNA, BacterialTranscriptional Elongation FactorsTranscription FactorsRho-dependent terminationRNA polymerase

Identifiers

PMID34705601
PMCPMC8632121

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.