Evidence map›Paper›PMID 34705561›Full record

ArticleJournal of virology2022

Characterization of M116.1p, a Murine Cytomegalovirus Protein Required for Efficient Infection of Mononuclear Phagocytes.

Tina Ružić, Vanda Juranić Lisnić, Hana Mahmutefendić Lučin, Tihana Lenac Roviš, Jelena Železnjak, Maja Cokarić Brdovčak, Ana Vrbanović, Deni Oreb, Daria Kveštak, Kristina Gotovac Jerčić and 5 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Immune surveillance of cytomegalovirus in tissues.Cellular & molecular immunology · 2024
    Review
  2. Article
  3. Decoding murine cytomegalovirus.PLoS pathogens · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 2 countries.

Tina Ružić *Center for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0002-1995-9620
Vanda Juranić Lisnić *Center for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.
Hana Mahmutefendić LučinDepartment of Physiology and Immunology, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0001-8462-4686
Tihana Lenac RovišCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0002-3299-1334
Jelena ŽeleznjakCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0001-6619-3675
Maja Cokarić BrdovčakCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0002-9335-8700
Ana VrbanovićCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.
Deni OrebCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.
Daria KveštakCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0001-5280-827X
Kristina Gotovac JerčićDepartment of Neurology, University Hospital Center Zagreb, Zagreb, Croatia.ORCID 0000-0001-5892-7392
Fran BorovečkiDepartment of Neurology, University Hospital Center Zagreb, Zagreb, Croatia.
Pero LučinDepartment of Physiology and Immunology, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0001-8776-8634
Barbara AdlerMax von Pettenkofer Institute & Gene Center, Virology, Faculty of Medicine, LMU Munich, Munich, Germany.
Stipan JonjićCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0001-5003-3108
Berislav LisnićCenter for Proteomics, Faculty of Medicine, University of Rijekagrid.22939.33, Rijeka, Croatia.ORCID 0000-0002-3977-6004
University of Rijeka · HRUniversity Hospital Centre Zagreb · HRLudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Broad tissue tropism of cytomegaloviruses (CMVs) is facilitated by different glycoprotein entry complexes, which are conserved between human CMV (HCMV) and murine CMV (MCMV). Among the wide array of cell types susceptible to the infection, mononuclear phagocytes (MNPs) play a unique role in the pathogenesis of the infection as they contribute both to the virus spread and immune control. CMVs have dedicated numerous genes for the efficient infection and evasion of macrophages and dendritic cells. In this study, we have characterized the properties and function of

Indexed as

AnimalsFibroblastsGlycosylationHerpesviridae InfectionsMembrane GlycoproteinsMiceMononuclear Phagocyte SystemMuromegalovirusTranscription, GeneticViral Envelope ProteinsVirionVirus AssemblyVirus InternalizationVirus ReplicationMembrane GlycoproteinsViral Envelope Proteinscytomegalovirusintranasal infectionmacrophagesmononuclear phagocytemouse cytomegalovirusviral assembly compartmentviral pathogenesisvirus entry

Identifiers

PMID34705561
PMCPMC8791281
OpenAlexW3209569655

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.