Evidence map›Paper›PMID 34705540›Full record

ArticleJournal of clinical microbiology2022

Genomic Analysis of a Hospital-Associated Outbreak of Mycobacterium abscessus: Implications on Transmission.

Rebecca M Davidson, Sophie E Nick, Sara M Kammlade, Sruthi Vasireddy, Natalia Weakly, Nabeeh A Hasan, L Elaine Epperson, Michael Strong, Jerry A Nick, Barbara A Brown-Elliott and 4 more

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Infection control and hospital epidemiology · 2026
    Article
  4. Genome and drug resistance analysis ofFrontiers in microbiology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Cluster ofFrontiers in veterinary science · 2025
    Article
  9. NGS-based approach for diagnostically unidentifiedFrontiers in cellular and infection microbiology · 2025
    Article
  10. Genomic epidemiology ofERJ open research · 2024
    Article
  11. Journal of clinical microbiology · 2024
    Article
  12. Article
  13. Article
  14. The problem of Mycobacterium abscessus complex: multi-drug resistance, bacteriophage susceptibility and potential healthcare transmission.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2023
    Article
  15. Article
  16. Review
  17. Molecular Epidemiologic Investigation ofAnnals of the American Thoracic Society · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Rebecca M DavidsonCenter for Genes, Environment and Health, National Jewish Healthgrid.240341.0, Denver, Colorado, USA.ORCID 0000-0001-7091-7963
Sophie E NickDuke University School of Medicinegrid.471396.e, Durham, North Carolina, USA.
Sara M KammladeCenter for Genes, Environment and Health, National Jewish Healthgrid.240341.0, Denver, Colorado, USA.
Sruthi VasireddyDepartment of Microbiology, The University of Texas Health Science Center at Tylergrid.267310.1, Tyler, Texas, USA.
Natalia WeaklyCenter for Genes, Environment and Health, National Jewish Healthgrid.240341.0, Denver, Colorado, USA.
Nabeeh A HasanCenter for Genes, Environment and Health, National Jewish Healthgrid.240341.0, Denver, Colorado, USA.
L Elaine EppersonCenter for Genes, Environment and Health, National Jewish Healthgrid.240341.0, Denver, Colorado, USA.
Michael StrongCenter for Genes, Environment and Health, National Jewish Healthgrid.240341.0, Denver, Colorado, USA.
Jerry A NickDepartment of Medicine, National Jewish Healthgrid.240341.0, Denver, Colorado, USA.
Barbara A Brown-ElliottDepartment of Microbiology, The University of Texas Health Science Center at Tylergrid.267310.1, Tyler, Texas, USA.ORCID 0000-0002-3091-1169
Jason E StoutDivision of Infectious Diseases, Duke University School of Medicinegrid.471396.e, Durham, North Carolina, USA.
Sarah S LewisDivision of Infectious Diseases, Duke University School of Medicinegrid.471396.e, Durham, North Carolina, USA.
Richard J WallaceDepartment of Microbiology, The University of Texas Health Science Center at Tylergrid.267310.1, Tyler, Texas, USA.
Arthur W BakerDivision of Infectious Diseases, Duke University School of Medicinegrid.471396.e, Durham, North Carolina, USA.

Funding

Transplant Infectious Diseases Interdisciplinary Research Training Grant (TIDIRTGT32AI100851 · NIAID · DUKE UNIVERSITY · PI ALEXANDER, BARBARA D · 2013 to 2022
$1.8M
Combined Use of Statistical Process Control and Whole Genome Sequencing to Detect and Investigate Nontuberculous Mycobacterial Clusters and OutbreaksK08AI163462 · NIAID · DUKE UNIVERSITY · PI BAKER, ARTHUR W · 2021 to 2025
$942k
Genetic Epidemiology of Nontuberculous Mycobacteria for Predicting Host Specificity and Lung Disease OutcomesK01AI125726 · NIAID · NATIONAL JEWISH HEALTH · PI DAVIDSON, REBECCA · 2016 to 2020
$557k
NIAID NIH HHS 5T32AI100851NIAID NIH HHS K01 AI125726NIAID NIH HHS K01-AI125726NIAID NIH HHS K08 AI163462NIAID NIH HHS T32 AI100851
6 · The paper itself

Abstract

Whole-genome sequencing (WGS) has recently been used to investigate acquisition of Mycobacterium abscessus. Investigators have reached conflicting conclusions about the meaning of genetic distances for interpretation of person-to-person transmission. Existing genomic studies were limited by a lack of WGS from environmental M. abscessus isolates. In this study, we retrospectively analyzed the core and accessory genomes of 26 M. abscessus subsp.

Indexed as

Cross InfectionDisease OutbreaksMycobacterium abscessusMycobacterium Infections, NontuberculousGenomicsHospitalsHumansRetrospective Studieshospital outbreakinfection preventionMycobacterium abscessusnontuberculous mycobacteriawhole-genome sequencing

Identifiers

PMID34705540
PMCPMC8769749

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.