Evidence map›Paper›PMID 34705536›Full record

ArticleJournal of clinical microbiology2022

Multicenter Clinical Evaluation of Vitek 2 Meropenem-Vaborbactam for Susceptibility Testing of

Hari P Dwivedi, Simone Franklin, Sukantha Chandrasekaran, Omai Garner, Maria M Traczewski, Denise Beasley, Gary W Procop, Marion Tuohy, Deborah Wilson, Yohann Bala and 1 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.3field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Evidence-Based Treatment ofAntibiotics (Basel, Switzerland) · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Hari P DwivedibioMérieux, Inc., Hazelwood, Missouri, USA.ORCID 0000-0001-5373-3361
Simone FranklinbioMérieux, Inc., Hazelwood, Missouri, USA.
Sukantha ChandrasekaranDepartment of Pathology and Laboratory Medicine, University of California-Los Angeles, California, USA.ORCID 0000-0002-6232-5535
Omai GarnerDepartment of Pathology and Laboratory Medicine, University of California-Los Angeles, California, USA.ORCID 0000-0002-7366-2692
Maria M TraczewskiClinical Microbiology Institute, Inc., Wilsonville, Oregon, USA.
Denise BeasleyClinical Microbiology Institute, Inc., Wilsonville, Oregon, USA.
Gary W ProcopPathology and Laboratory Medicine Institute, Cleveland Clinicgrid.239578.2, Cleveland, Ohio, USA.ORCID 0000-0002-3164-2968
Marion TuohyPathology and Laboratory Medicine Institute, Cleveland Clinicgrid.239578.2, Cleveland, Ohio, USA.
Deborah WilsonPathology and Laboratory Medicine Institute, Cleveland Clinicgrid.239578.2, Cleveland, Ohio, USA.
Yohann BalabioMérieux SA, Marcy l'Etoile, France.
David H PincusbioMérieux, Inc., Hazelwood, Missouri, USA.
bioMérieux (United States) · USCleveland Clinic · USHuman BioMolecular Research Institute · USUniversity of California, Los Angeles · USbioMérieux (France) · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The carbapenem/beta-lactamase inhibitor meropenem-vaborbactam (MEV) used to treat complicated urinary tract infections and pyelonephritis in adults was approved in 2017 by the U.S. Food and Drug Administration (FDA). Here, we evaluated Vitek 2 MEV (bioMérieux, Durham, NC) compared to the reference broth microdilution (BMD) method. Of 449 Enterobacterales isolates analyzed per FDA/CLSI breakpoints, the overall performance was 98.2% essential agreement (EA), 98.7% category agreement (CA), and 0% very major errors (VME) or major errors (ME). For 438 FDA intended-for-use

Indexed as

Anti-Bacterial AgentsPseudomonas aeruginosaBoronic AcidsHumansMeropenemMicrobial Sensitivity TestsAnti-Bacterial AgentsBoronic AcidsMeropenemvaborbactamASTautomated susceptibility testingmeropenem-vaborbactamVitek 2

Identifiers

PMID34705536
PMCPMC8769728
OpenAlexW3209594548

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.