Evidence map›Paper›PMID 34705528›Full record

ReviewThe British journal of radiology2022

Effect of metformin on

Xieyi Zhang, Takuo Ogihara, Min Zhu, Dolgormaa Gantumur, Yang Li, Kenta Mizoi, Hiroki Kamioka, Yoshito Tsushima

Open access · bronzeAbstract readReview
In one paragraph

Review in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Impact of biguanide therapy on hepaticAnnals of nuclear medicine · 2026
    Article
  3. Feasibility of Early DynamicMolecular imaging and biology · 2025
    Article
  4. Article
  5. Article
  6. Dual-Time-PointBMC cancer · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Xieyi ZhangLaboratory of Biopharmaceutics, Department of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan.ORCID 0000-0002-3421-5398
Takuo OgiharaLaboratory of Biopharmaceutics, Department of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan.
Min ZhuWeifang Community Health Service Center, Pudong New District, Shanghai, China.
Dolgormaa GantumurDepartment of Hepatobiliary and Pancreatic Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.
Yang LiGunma University Heavy Ion Medical Center, Maebashi, Gunma, Japan.
Kenta MizoiLaboratory of Biopharmaceutics, Department of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan.
Hiroki KamiokaLaboratory of Biopharmaceutics, Department of Pharmacology, Faculty of Pharmacy, Takasaki University of Health and Welfare, Takasaki, Gunma, Japan.
Yoshito TsushimaDepartment of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan.
Gunma University · JPTakasaki University of Health and Welfare · JPGunma University Hospital · JPPudong New Area People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metformin is widely used to treat diabetes, but induces changes in glucose uptake in both normal organs and tumors. Here, we review the effects of metformin on the uptake of

Indexed as

Positron-Emission TomographyAnimalsBreast NeoplasmsCarcinoma, HepatocellularColonic NeoplasmsDiabetes Mellitus, Type 2Energy IntakeFemaleFluorodeoxyglucose F18Gastrointestinal TractGlucoseHumansHyperglycemiaHypoglycemic AgentsKidneyLiver NeoplasmsFluorodeoxyglucose F18GlucoseHypoglycemic AgentsMetforminRadiopharmaceuticals

Identifiers

PMID34705528
PMCPMC8822544
OpenAlexW3209512691

What OpenQuestion holds

Texttitle and abstract
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.