Evidence map›Paper›PMID 34705425›Full record

ArticleACS nano2021

Gold-Nanostar-Chitosan-Mediated Delivery of SARS-CoV-2 DNA Vaccine for Respiratory Mucosal Immunization: Development and Proof-of-Principle.

Uday S Kumar, Rayhaneh Afjei, Katherine Ferrara, Tarik F Massoud, Ramasamy Paulmurugan

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in ACS nano, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 93 citations in OpenAlex.

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  17. Nanotechnology of inhalable vaccines for enhancing mucosal immunity.Drug delivery and translational research · 2024
    Review
  18. Review
  19. Review
  20. Chitosan non-particulate vaccine delivery systems.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2024
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Uday S KumarMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, California 94305, United States.
Rayhaneh AfjeiMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, California 94305, United States.
Katherine FerraraMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0002-4976-9107
Tarik F MassoudMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0002-9694-1408
Ramasamy PaulmuruganMolecular Imaging Program at Stanford (MIPS), Department of Radiology, Stanford University School of Medicine, Stanford, California 94305, United States.ORCID 0000-0001-7155-4738
Stanford University · US

Funding

Celigo S Imaging Cytometer (200-BFFL-S)S10OD023518 · OD · STANFORD UNIVERSITY · PI PAULMURUGAN, RAMASAMY · 2018 to 2018
$174k
NIH HHS S10 OD023518
6 · The paper itself

Abstract

The COVID-19 pandemic is caused by the coronavirus SARS-CoV-2 (SC2). A variety of anti-SC2 vaccines have been approved for human applications, including those using messenger RNA (mRNA), adenoviruses expressing SC2 spike (S) protein, and inactivated virus. The protective periods of immunization afforded by these intramuscularly administered vaccines are currently unknown. An alternative self-administrable vaccine capable of mounting long-lasting immunity

Indexed as

ChitosanCOVID-19Vaccines, DNAViral VaccinesAnimalsAntibodies, NeutralizingAntibodies, ViralCOVID-19 VaccinesGoldHumansImmunizationImmunoglobulin AMiceMice, Inbred BALB CMice, Inbred C57BLPandemicsAntibodies, NeutralizingAntibodies, ViralChitosanCOVID-19 VaccinesGoldImmunoglobulin AVaccines, DNAViral VaccineschitosanCOVID-19DNA vaccinegold nanoparticlesintranasal deliverymRNA vaccineSARS-CoV-2

Identifiers

PMID34705425
PMCPMC8565460
OpenAlexW3209235379

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.