Evidence map›Paper›PMID 34705424›Full record

ArticleAnalytical chemistry2021

UniDecCD: Deconvolution of Charge Detection-Mass Spectrometry Data.

Marius M Kostelic, Ciara K Zak, Yang Liu, Victor Shugui Chen, Zhuchun Wu, Jared Sivinski, Eli Chapman, Michael T Marty

Open access · greenAbstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 36 citations in OpenAlex.

  1. Design of Fluorescent Membrane Scaffold Proteins for Nanodiscs.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. To 200,000ACS central science · 2024
    Article
  11. Article
  12. Article
  13. Article
  14. Do Nanodisc Assembly Conditions Affect Natural Lipid Uptake?Journal of the American Society for Mass Spectrometry · 2023
    Article
  15. Article
  16. Article
  17. Review
  18. Allosteric differences dictate GroEL complementation of E. coli.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Marius M KostelicDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Ciara K ZakDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.
Yang LiuREGENXBIO Inc., 9804 Medical Center Dr, Rockville, Maryland 20850, United States.
Victor Shugui ChenREGENXBIO Inc., 9804 Medical Center Dr, Rockville, Maryland 20850, United States.
Zhuchun WuREGENXBIO Inc., 9804 Medical Center Dr, Rockville, Maryland 20850, United States.
Jared SivinskiDepartment of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona 85721, United States.
Eli ChapmanDepartment of Pharmacology and Toxicology, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0002-6310-1664
Michael T MartyDepartment of Chemistry and Biochemistry, University of Arizona, Tucson, Arizona 85721, United States.ORCID 0000-0001-8115-1772
University of Arizona · USRegenxbio (United States) · US

Funding

CHEMISTRY-BIOLOGY INTERFACE TRAINING PROGRAMT32GM008804 · NIGMS · UNIVERSITY OF ARIZONA · PI MONTFORT, WILLIAM R. · 2003 to 2023
$3.9M
NIGMS NIH HHS T32 GM008804
6 · The paper itself

Abstract

Native mass spectrometry (MS) has become a versatile tool for characterizing high-mass complexes and measuring biomolecular interactions. Native MS usually requires the resolution of different charge states produced by electrospray ionization to measure the mass, which is difficult for highly heterogeneous samples that have overlapping and unresolvable charge states. Charge detection-mass spectrometry (CD-MS) seeks to address this challenge by simultaneously measuring the charge and

Indexed as

ProteinsSpectrometry, Mass, Electrospray IonizationAlgorithmsIonsSoftwareIonsProteins

Identifiers

PMID34705424
PMCPMC8628365
OpenAlexW3209593844

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.