Evidence map›Paper›PMID 34705341›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2021

Patterned Electrode Assisted One-Step Fabrication of Biomimetic Morphing Hydrogels with Sophisticated Anisotropic Structures.

Qing Li Zhu, Chen Fei Dai, Daniel Wagner, Olena Khoruzhenko, Wei Hong, Josef Breu, Qiang Zheng, Zi Liang Wu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Hydrogel-based neural engineering for skin wound healing.Frontiers in cell and developmental biology · 2026
    Review
  3. Article
  4. Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Light-Fueled Hydrogel Actuators with Controlled Deformation and Photocatalytic Activity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qing Li ZhuMinistry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
Chen Fei DaiMinistry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
Daniel WagnerBavarian Polymer Institute and Department of Chemistry, University of Bayreuth, Universitätsstrasse 30, Bayreuth, 95440, Germany.
Olena KhoruzhenkoBavarian Polymer Institute and Department of Chemistry, University of Bayreuth, Universitätsstrasse 30, Bayreuth, 95440, Germany.
Wei HongDepartment of Mechanics and Aerospace Engineering, Southern University of Science and Technology, Shenzhen, 518055, China.ORCID 0000-0001-6598-3456
Josef BreuBavarian Polymer Institute and Department of Chemistry, University of Bayreuth, Universitätsstrasse 30, Bayreuth, 95440, Germany.ORCID 0000-0002-2547-3950
Qiang ZhengMinistry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China.
Zi Liang WuMinistry of Education Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, China.ORCID 0000-0002-1824-9563

Funding

DFG SFB 840 (B3)National Natural Science Foundation of China 51773179National Natural Science Foundation of China 51973189Natural Science Foundation of Zhejiang Province of China LR19E030002
6 · The paper itself

Abstract

Anisotropic structures are ubiquitous in nature, affording fascinating morphing behaviors. Biomimetic morphing materials can be developed by spatially controlling the orientations of molecules or nanofillers that produce anisotropic responses and internal stresses under external stimuli. However, it remains a serious challenge to fabricate materials with sophisticated anisotropic architectures. Here, a facile strategy to fabricate morphing hydrogels with elaborately ordered structures of nanosheets, which are oriented under distributed electric field and immobilized by polymerization to form a poly(N-isopropylacrylamide) matrix, is proposed. Diverse sophisticated anisotropic structures are obtained by engineering the electric field through the patterns and relative locations of the electrodes. Upon heating, the monolithic hydrogels with through-thickness and/or in-plane gradients in orientation of the nanosheets deform into various three-dimensional configurations. After incorporating gold nanoparticles, the hydrogels become photoresponsive and capable of programmable motions, for example, dynamic twisting and flipping under spatiotemporal stimuli. Such a strategy of using patterned electrodes to generate distributed electric field should be applicable to systems of liquid crystals or charged particles/molecules to direct orientation or electrophoresis and form functional structures. The biomimetically architectured hydrogels would be ideal materials to develop artificial muscles, soft actuators/robots, and biomedical devices with versatile applications.

Indexed as

AnisotropyBiomimetic MaterialsBiomimeticsElectrodesHydrogelsHydrogelsbiomimetic structureselectrical orientationshydrogelsmorphing materialssoft actuators

Identifiers

PMID34705341
PMCPMC8693068

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.