Evidence map›Paper›PMID 34705166›Full record

ArticleAmerican journal of clinical dermatology2022

Impact of Facial Atrophic Acne Scars on Quality of Life: A Multi-country Population-Based Survey.

Jerry Tan, Stefan Beissert, Fran Cook-Bolden, Rajeev Chavda, Julie Harper, Adelaide Hebert, Edward Lain, Alison Layton, Marco Rocha, Jonathan Weiss and 1 more

Open access · hybridAbstract read
In one paragraph

Article in American journal of clinical dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 5 pooled it
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 5 syntheses or guidelines pooled it, 55 citations in OpenAlex.

  1. Pooled it
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  17. Article
  18. Stigmatization and Psychosocial Burden in Acne Patients.Journal of cosmetic dermatology · 2025
    Article
  19. Dual-Plane Treatment With Highly Concentrated Hybrid Cooperative Complexes of Hyaluronans for Facial Atrophic Acne Scars.Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] · 2025
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 6 countries.

Jerry Tan, 2224 Walker Road, Suite 300, Windsor, ON, N8W 5L7, Canada.
Stefan BeissertDepartment of Dermatology, University Hospital Carl Gustav Carus, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Fran Cook-BoldenMount Sinai Department of Dermatology, 5 East 98th Street, New York, NY, 10029, USA.
Rajeev ChavdaGALDERMA, Rue d'Entre-deux-Villes 10, 1814, La Tour-de-Peilz, Switzerland.
Julie HarperThe Dermatology and Skin Care Center of Birmingham, 2470 Rocky Ridge Rd # 100, Vestavia Hills, AL, 35243, USA.
Adelaide HebertThe University of Texas Medical School-Houston, 6655 Travis, Suite 980, Houston, TX, 77030, USA.
Edward LainAustin Institute for Clinical Research, 1601 E Pflugerville Pkwy Suite 1101, Pflugerville, TX, USA.
Alison LaytonHull York Medical School, University Rd, Heslington, YO10 5DD, York, UK.
Marco RochaFederal University of São Paulo, R. Sena Madureira, 1500-Vila Clementino, São Paulo, SP, 04021-001, Brazil.
Jonathan WeissGeorgia Dermatology Partners, (Formerly, Gwinnett Dermatology, PC), 2383 Pate St., N, Snellville, GA, 30078, USA.
Brigitte DrénoUnité Thérapie Cellulaire et Génique, Faculté de Médecine de Nantes, CHU Nantes-Place Alexis Ricordeau, 44093, Nantes Cedex 01, France. brigitte.dreno@atlanmed.fr.
Centre Hospitalier Universitaire de Nantes · FRGalderma (Switzerland) · CHGold Skin Care Center · USGwinnett Dermatology · USHull York Medical School · GBUniversidade Federal de São Paulo · BRUniversity Hospital Carl Gustav Carus · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcne affects more than 80% of adolescents and young adults, who most often develop acne scars. Supporting data on the effect of acne scars on patient's health-related quality of life (HRQOL) are limited.

objectiveThe aim was to determine how the severity of acne scars impacts the HRQOL of afflicted individuals.

methodsIn this population-based cross-sectional study, 723 adults with facial acne scars but without active acne lesions self-completed the Self-assessment of Clinical Acne-Related Scars (SCARS) questionnaire formulated to investigate degree of acne scarring. The Facial Acne Scar Quality of Life (FASQoL), Dermatology Life Quality Index (DLQI), and Dysmorphic Concern Questionnaire (DCQ) were completed to assess the attitude of these patients toward their scars and the impact of scarring on their HRQOL.

resultsThe mean (standard error) DLQI score for facial acne scars was 6.26 (0.22). Acne scars were considered a 'very large' or 'extremely large' concern by 19.3% of participants with mild scars as compared to 20.1% and 34.0% of participants with moderate and severe/very severe scars, respectively (P = 0.003). Higher FASQoL scores were associated with increased severity of scarring (P = 0.001). In total, 16.9% of participants had clinical features of dysmorphia (i.e., DCQ > 13). DCQ scores were significantly higher among participants with more severe scarring (mean DCQ score of 8.04 [0.28], 8.40 [0.18], and 10.13 [0.08] among participants with mild, moderate, and severe/very severe acne scars, respectively; P = 0.001). Most commonly reported signs of emotional distress were self-consciousness (68.0%) and worry about scars not going away (74.8%).

conclusionsThis study highlights the significant psychosocial impact of atrophic acne scars in the form of embarrassment and self-consciousness. Individuals with mild scars also expressed significant impact on quality of life that increased with aggravation of scar severity. Patient-reported outcomes provide an insight into the physical, functional, and psychological impact of acne scarring from the patient's perspective.

Indexed as

Quality of LifeAcne VulgarisAdolescentAdultCicatrixCross-Sectional StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesYoung Adult

Identifiers

PMID34705166
PMCPMC8776674
OpenAlexW3209615412

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.