ReviewSchmerz (Berlin, Germany)2022
[The effect of treatment expectations on pruritus and skin pain].
Review in Schmerz (Berlin, Germany), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Beyond pharmacology: The mediating role of expectations in the experience of side effects in anxious patients treated with secukinumab.Brain, behavior, & immunity - health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPatients' expectations in terms of the benefit of a treatment are key determinants of placebo responses and can affect the development and course of medical conditions as well as the efficacy and tolerability of active medical treatment. The mechanisms mediating these placebo and nocebo effects have been best described in the field of experimental pain and placebo analgesia. However, also in dermatology experimental and clinical studies demonstrate that different skin symptoms such as itch, skin pain and dermatologic diseases can be modulated by patients' expectations.
objectivesThe aim of this review is to provide a current overview of the empirical evidence for the effects of patients' expectations in the field of dermatology with a focus on different skin symptoms such as itch and pain. Finally, the relevance of this topic for physicians who treat patients with dermatologic symptoms is discussed. MATERIALS AND
methodsThe article is a narrative review.
resultsSteadily growing evidence from experimental and clinical studies in healthy volunteers and dermatologic patients suggests that patients' positive treatment expectations can reduce skin disease symptoms and enhance treatment efficacy, while negative treatment expectations can induce a nocebo effect associated with increased symptomatology. Patients' prior treatment experiences as well as the quality and quantity of doctor-patient communication play a central role in shaping treatment expectations.
conclusionsTechniques aimed at maximizing positive expectation effects in patients should be implemented in daily clinical routine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.