ArticleRenal failure2021
Normotensive and hypertensive Immunoglobulin a nephropathy with ischemic renal injury: clinicopathological characteristics and prognosis.
Article in Renal failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 9 citations in OpenAlex.
- Renal and cardiovascular prognostic significance of echocardiographic early diastolic mitral annular velocity in IgA nephropathy.The international journal of cardiovascular imaging · 2024Article
- Relationship between arterial stiffness, left ventricular diastolic function, and renal function in chronic kidney disease.BMC nephrology · 2023Article
- Arteriolar hyalinosis and renal outcomes in patients with immunoglobulin A nephropathy.Renal failure · 2022Article
- Visit-to-visit variability in blood pressure and kidney disease progression in IgA nephropathy.Clinical kidney journal · 2022Article
- Left ventricular myocardial mass index associated with cardiovascular and renal prognosis in IgA nephropathy.BMC nephrology · 2022Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
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Abstract
objectivesThis study aimed to investigate the clinicopathological characteristics and prognosis of normotensive and hypertensive IgAN patients with ischemic renal injury.
methodsA total of 344 cases of IgAN with ischemic renal injury were included in the study, including 99 normotensive IgAN patients (28.8%) and 245 hypertensive IgAN patients (71.2%). In addition, 467 IgAN patients without ischemic renal injury were included as controls, including 205 normotensive patients and 262 hypertensive patients. Clinicopathological and prognostic data were collected and analyzed.
resultsCompared with patients without ischemic renal injury, IgAN patients with ischemic renal injury displayed a higher proportion of hypertention, a higher proportion of ischemic glomerulosclerosis, tubular atrophy/interstitial fibrosis and vascular lesions (all
conclusionsIschemic renal injury can occur in normotensive IgAN patients. Although the pathological changes may not affect the long-term prognosis of normotensive IgAN patients, the prognosis for hypertensive IgAN patients remains poor. Therefore, increased attention should be paid to the clinical management of ischemic lesions in hypertensive IgAN patients.
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