Evidence map›Paper›PMID 34704852›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2021

Inflammatory phenotype modulation in the respiratory tract and systemic circulation of e-cigarette users: a pilot study.

Ibrahim M Sayed, Jorge A Masso-Silva, Ankita Mittal, Arjun Patel, Erica Lin, Alex Moshensky, John Shin, Christine M Bojanowski, Soumita Das, Praveen Akuthota and 1 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  15. A Problem for Generations: Impact of E-Cigarette Type on Immune Homeostasis.American journal of respiratory and critical care medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Ibrahim M SayedDepartment of Pathology, University of California San Diego, La Jolla, California.
Jorge A Masso-SilvaSection of Pulmonary and Critical Care Medicine, Veterans Affairs San Diego Healthcare System, La Jolla, California.
Ankita MittalDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California San Diego, La Jolla, California.
Arjun PatelSection of Pulmonary and Critical Care Medicine, Veterans Affairs San Diego Healthcare System, La Jolla, California.ORCID 0000-0003-4631-899X
Erica LinSection of Pulmonary and Critical Care Medicine, Veterans Affairs San Diego Healthcare System, La Jolla, California.ORCID 0000-0002-7522-782X
Alex MoshenskySection of Pulmonary and Critical Care Medicine, Veterans Affairs San Diego Healthcare System, La Jolla, California.
John ShinSection of Pulmonary and Critical Care Medicine, Veterans Affairs San Diego Healthcare System, La Jolla, California.
Christine M BojanowskiSection of Pulmonary Diseases, Critical Care and Environmental Medicine, Tulane University, New Orleans, Louisiana.
Soumita DasDepartment of Pathology, University of California San Diego, La Jolla, California.ORCID 0000-0003-3895-3643
Praveen AkuthotaDivision of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California San Diego, La Jolla, California.
Laura E Crotty AlexanderSection of Pulmonary and Critical Care Medicine, Veterans Affairs San Diego Healthcare System, La Jolla, California.ORCID 0000-0002-5091-2660
University of California System · USUniversity of California San Diego · USTulane University · USVA San Diego Healthcare System · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Leigh Lamonica · 2012 to 2026
$69.1M
Macrophage Polarization in Response to Infections and InflammationR01AI155696 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI GHOSH, PRADIPTA, SAHOO, DEBASHIS · 2020 to 2024
$4.9M
Innate responses following infection with enteric microbesR01DK107585 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DAS, SOUMITA · 2016 to 2020
$2.2M
Joint Initiative in Vaccine Economics 5U01IP000965 · IP · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HUTTON, DAVID W · 2015 to 2017
$899k
Hypoxia inducible factors in pulmonary endothelial cells regulate allergic inflammatory airways diseaseI01BX004767 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI CROTTY ALEXANDER, LAURA ELISE · 2020 to 2023
–
BLRD VA I01 BX004767HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) R01-HL13705201HHS | NIH | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) DK107585NCIRD CDC HHS U01 IP000965NIAID NIH HHS R01 AI155696NIDDK NIH HHS R01 DK107585NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Over 40 million people use e-cigarettes worldwide, but the impact of chronic e-cigarette use on health has not been adequately defined. In particular, effects of e-cigarette aerosol inhalation on inflammation and host defenses across the body are not fully understood. We conducted a longitudinal cohort pilot study to explore changes in the inflammatory state and monocyte function of e-cigarette users (

Indexed as

AdolescentAdultCase-Control StudiesCytokinesElectronic Nicotine Delivery SystemsFemaleHumansInflammationLongitudinal StudiesMalePilot ProjectsPlasmaRespiratory SystemSalivaSmokeSputumCytokinesSmokecytokinee-cigarettehost defenseinflammationmonocyte

Identifiers

PMID34704852
PMCPMC8715026
OpenAlexW3208314218

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.