Evidence map›Paper›PMID 34704785›Full record

ArticleMicrobiology spectrum2021

Tandem Mass Tag-Based Quantitative Proteomics and Virulence Phenotype of Hemolymph-Treated Bacillus thuringiensis kurstaki Cells Reveal New Insights on Bacterial Pathogenesis in Insects.

Yanyan Sun, Linlin Yang, Lianet Rodríguez-Cabrera, Yushan Ding, Chaoliang Leng, Huili Qiao, Siliang Huang, Yunchao Kan, Lunguang Yao, Denis J Wright and 2 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Yanyan Sun *China-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Linlin Yang *China-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Lianet Rodríguez-CabreraPlant Division, Centre for Genetic Engineering and Biotechnology (CIGB), Havana, Cuba.
Yushan DingChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Chaoliang LengChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Huili QiaoChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Siliang HuangChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Yunchao KanChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Lunguang YaoChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Denis J WrightDepartment of Life Sciences, Faculty of Natural Sciences, Imperial College Londongrid.7445.2, Ascot, United Kingdom.
Dandan LiChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.
Camilo Ayra-PardoChina-UK-NYNU-RRES Joint Laboratory of Insect Biology, Henan Key Laboratory of Insect Biology in Funiu Mountain, School of Life Sciences and Agricultural Engineering, Nanyang Normal Universitygrid.453722.5 (NYNU), Nanyang, People's Republic of China.ORCID 0000-0001-5579-677X
Nanyang Normal University · CNCentro de Ingeniería Genética y Biotecnología · CUImperial College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spore-forming bacterium Bacillus thuringiensis (Bt) of the Bacillus cereus group uses toxin-opened breaches at the insect midgut epithelium to infest the hemolymph, where it can rapidly propagate despite antimicrobial host defenses and induce host death by acute septicemia. The response of Bt to host hemolymph and the latter's role in bacterial pathogenesis is an area that needs clarification. Here, we report a proteomic analysis of the Bt

Indexed as

HemolymphPhenotypeProteomicsAnimalsBacillus thuringiensisBacterial ProteinsBiofilmsFemaleImmune EvasionInsectaMiceMice, Inbred BALB COxidative StressVirulenceVirulence FactorsBacterial ProteinsVirulence Factorsbiofilm formationbiofilmsimmune evasioninsect pathogenoxidative stresspersistenceproteomicssepticemiaTMT-based quantitative proteomicsvirulence

Identifiers

PMID34704785
PMCPMC8549738
OpenAlexW3211283361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.