Evidence map›Paper›PMID 34704753›Full record

ArticleBiomacromolecules2021

Nanoparticles To Study Lectins in

Harrison W VanKoten, Rebecca S Moore, Mary J Cloninger

Open access · greenAbstract read
In one paragraph

Article in Biomacromolecules, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Immunodominant IgM Epitopes of theInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Harrison W VanKotenDepartment of Chemistry and Biochemistry, Montana State University, 103 Chemistry and Biochemistry Building, Bozeman, Montana 59717, United States.
Rebecca S MooreDepartment of Molecular Biology & LSI Genomics, Princeton University, Princeton, New Jersey 08544, United States.
Mary J CloningerDepartment of Chemistry and Biochemistry, Montana State University, 103 Chemistry and Biochemistry Building, Bozeman, Montana 59717, United States.ORCID 0000-0002-7551-1003
Montana State University · USPrinceton University · US

Funding

Using Dendrimers to Design Multivalent Therapeutic AgentsR01GM062444 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI CLONINGER, MARY J · 2001 to 2015
$3.5M
NIGMS NIH HHS R01 GM062444
6 · The paper itself

Abstract

Galectins are galactoside-binding lectins that are functional dimers or higher-order oligomers. Multivalent binding has been shown to augment the relatively low affinity of the galectins for their galactoside-binding partners, enabling the galectins to play an important role in the global remodeling of cells that occurs during the stress conditions of disease states, including heart disease and cancer. The presence of galectins in the nematode

Indexed as

Caenorhabditis elegans ProteinsDendrimersAnimalsCaenorhabditis elegansFucoseGalactoseGalectinsOxidative StressCaenorhabditis elegans ProteinsDendrimersFucoseGalactoseGalectins

Identifiers

PMID34704753
PMCPMC8882377
OpenAlexW3209970080

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.