Evidence map›Paper›PMID 34704664›Full record

ArticleChemistryOpen2021

Flavonoids in Lemon and Grapefruit IntegroPectin*.

Antonino Scurria, Marzia Sciortino, Lorenzo Albanese, Domenico Nuzzo, Federica Zabini, Francesco Meneguzzo, Rosa Alduina, Alessandro Presentato, Mario Pagliaro, Giuseppe Avellone and 1 more

Open access · goldAbstract read
In one paragraph

Article in ChemistryOpen, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Exploring Phenolic Compounds in Crop By-Products for Cosmetic Efficacy.International journal of molecular sciences · 2024
    Review
  4. Article
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Antonino ScurriaIstituto per lo Studio dei Materiali Nanostrutturati, CNR, via U. La Malfa 153, 90146, Palermo, Italy.ORCID 0000-0001-5624-6833
Marzia SciortinoDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, via Archirafi 32, 90123, Palermo, Italy.ORCID 0000-0002-2805-4452
Lorenzo AlbaneseIstituto per la Bioeconomia, CNR, via Madonna del Piano 10, 50019, Sesto Fiorentino (FI), Italy.ORCID 0000-0002-4549-8514
Domenico NuzzoIstituto per la Ricerca e l'innovazione Biomedica, CNR, via U. La Malfa 153, 90146, Palermo, Italy.ORCID 0000-0002-4325-417X
Federica ZabiniIstituto per la Bioeconomia, CNR, via Madonna del Piano 10, 50019, Sesto Fiorentino (FI), Italy.ORCID 0000-0003-1505-0839
Francesco MeneguzzoIstituto per la Bioeconomia, CNR, via Madonna del Piano 10, 50019, Sesto Fiorentino (FI), Italy.ORCID 0000-0002-5952-9166
Rosa AlduinaDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, viale delle Scienze, Ed.16, 90128, Palermo, Italy.ORCID 0000-0003-1054-6915
Alessandro PresentatoDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, viale delle Scienze, Ed.16, 90128, Palermo, Italy.ORCID 0000-0002-4794-0599
Mario PagliaroIstituto per lo Studio dei Materiali Nanostrutturati, CNR, via U. La Malfa 153, 90146, Palermo, Italy.ORCID 0000-0002-5096-329X
Giuseppe AvelloneDipartimento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Università di Palermo, via Archirafi 32, 90123, Palermo, Italy.ORCID 0000-0002-4539-6059
Rosaria CiriminnaIstituto per lo Studio dei Materiali Nanostrutturati, CNR, via U. La Malfa 153, 90146, Palermo, Italy.ORCID 0000-0001-6596-1572
University of Palermo · ITInstitute of Nanostructured Materials · ITIstituto per la Valorizzazione del Legno e delle Specie Arboree · ITInstitute for Biomedical Research and Innovation · IT

Funding

IntegroPectinOPAC Campisi (Siracusa, Italy)
6 · The paper itself

Abstract

Following the analysis of terpenes present in new lemon and grapefruit "IntegroPectin" pectins obtained via the hydrodynamic cavitation of industrial lemon and grapefruit processing waste, the HPLC-MS analysis of flavonoid and other phenolic compounds reveals the presence of eriocitrin, naringin, hesperidin and kaempferol typical of the respective citrus fruits. The pectic fibers rich in rhamnogalacturonan-I regions act as chemical sponges adsorbing and concentrating at their outer surface highly bioactive citrus flavonoids and terpenes. These findings, together with the unique molecular structure of these new whole citrus pectins, provide preliminary insight into the broad-scope biological activity of these new biomaterials. Numerous new biomedical applications are anticipated, including likely use in the prevention and treatment of microbial infections and neurodegenerative disease.

Indexed as

CitrusCitrus paradisiNeurodegenerative DiseasesFlavonoidsFruitFlavonoidscitrus fruitsflavonoidshydrodynamic cavitationIntegroPectinpectins

Identifiers

PMID34704664
PMCPMC8549029
OpenAlexW3209513953

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.