Evidence map›Paper›PMID 34704644›Full record

ArticleJournal of magnetic resonance imaging : JMRI2022

Quality Control of Magnetic Resonance Elastography Using Percent Measurable Liver Volume Estimation.

David H Ballard, Daniel R Ludwig, Tyler J Fraum, Amber Salter, Vamsi R Narra, Anup S Shetty

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

David H BallardMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.ORCID 0000-0001-7470-3364
Daniel R LudwigMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Tyler J FraumMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Amber SalterDivision of Biostatistics, Washington University School of Medicine, St. Louis, Missouri, USA.
Vamsi R NarraMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.
Anup S ShettyMallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, USA.

Funding

Training OPportunities in Translational Imaging Education and Research (TOP-TIER)T32EB021955 · NIBIB · WASHINGTON UNIVERSITY · PI Hongyu An, Joseph Edward Ippolito · 2017 to 2026
$2.4M
NIBIB NIH HHS T32 EB021955
6 · The paper itself

Abstract

backgroundAlthough studies have described factors associated with failed magnetic resonance elastography (MRE), little is known about what factors influence usable elastography data. PURPOSE: To identify factors that have a negative impact on percent measurable liver volume (pMLV), defined as the proportion of usable liver elastography data relative to the volume of imaged liver in patients undergoing MRE. STUDY TYPE: Retrospective. SUBJECTS: A total of 264 patients (n = 132 males, n = 132 females; mean age = 57 years) with suspected or known chronic liver disease underwent MRE paired with a liver protocol MRI. FIELD STRENGTH/SEQUENCE: MRE was performed on a single 1.5 T scanner using a two-dimensional gradient-recalled echo phase-contrast sequence with a passive acoustic driver overlying the right hemiliver. ASSESSMENT: Stiffness maps (usable data at 95% confidence) and liver contours on magnitude images of the MRE acquisition were manually traced and used to assess mean stiffness and pMLV. Hepatic fat fraction and R STATISTICAL TESTS: Linear regression was performed to identify factors significantly associated with pMLV. Intraclass correlation was performed for inter-reader reliability.

resultspMLV was 31% ± 20% (range 0%-86%). Complete MRE failure (i.e. pMLV = 0%) occurred in 10 patients (4%). Multivariate linear regression identified higher hepatic fat fraction, R DATA

conclusionHigher fat fraction, R LEVEL OF EVIDENCE: 3 TECHNICAL EFFICACY STAGE: 2.

Indexed as

Elasticity Imaging TechniquesFemaleHumansLiverLiver CirrhosisMagnetic Resonance ImagingMaleMiddle AgedQuality ControlReproducibility of ResultsRetrospective Studieselastographyhepatic steatosisliver fibrosismagnetic resonance elastographyproton density fat fraction

Identifiers

PMID34704644
PMCPMC9043030

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.