ArticleJournal of veterinary internal medicine2021
Evaluation of hair and nail cortisol concentrations and associations with behavioral, physical, and environmental indicators of chronic stress in cats.
Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 30 citations in OpenAlex.
- A Validated LC-MS/MS Method for Simultaneous Determination of Cortisol and Cortisone in Grey Wolf Hair for Application in Ecological Studies.Molecules (Basel, Switzerland) · 2026Article
- Beyond the Mission: Long-Term Endocrine Dynamics in Search and Rescue Dog-Handler Teams.Animals : an open access journal from MDPI · 2026Article
- Assessing Cat Welfare: A Literature Review on Behavioural, Physiological and Health Parameters with a Focus on Animal-Assisted Services (AAS).Veterinary sciences · 2026Review
- Effects of Social Interactions and Foundational Training on Behavior, Temperament, and Hormone Levels in Weanling Horses.Animals : an open access journal from MDPI · 2026Article
- Factors affecting hair cortisol concentration in privately owned intact cats.Frontiers in veterinary science · 2026Article
- Alpha-Amylase Activity in Feline Saliva: An Analytical Validation of an Automated Assay for Its Measurement and a Pilot Study on Its Changes Following Acute Stress and Due to Urinary Tract Pathologies.Animals : an open access journal from MDPI · 2025Article
- Claw growth rates in a subset of adult, indoor, domestic cats (Felis catus).Veterinary dermatology · 2025Article
- RETRACTED: Hair Cortisol and Fe-BARQ: Evaluating Chronic Stress and Behavior in Cats with Chronic Kidney Disease.Animals : an open access journal from MDPI · 2025Article
- Evaluation of chronic stress status and quality of life in cats suffering from chronic kidney disease and suspected feline infectious peritonitis based on hair cortisol concentration analysis and a questionnaire.The veterinary quarterly · 2024Article
- Hair cortisol concentrations in clipped and combed hair and associations with characteristics, health status and stress in domestic cats.Scientific reports · 2024Article
- The Impact of Environmental Enrichment on the Cortisol Level of Shelter Cats.Animals : an open access journal from MDPI · 2024Article
- A validated LC-MS/MS method for simultaneous determination of key glucocorticoids in animal hair for applications in conservation biology.Scientific reports · 2023Article
- Peripubertal Testosterone, 17β-Estradiol and Progesterone Concentrations in Hair and Nails in Dobermann Dogs.Animals : an open access journal from MDPI · 2023Article
- Coat, Claw and Dewclaw 17-β-Estradiol and Testosterone Concentrations in Male and Female Postpubertal Cats: Preliminary Results.Animals : an open access journal from MDPI · 2023Article
- Hair cortisol levels in cats with and without behavioural problems.Journal of feline medicine and surgery · 2023Article
- Assessing chronic stress in wild mammals using claw-derived cortisol: a validation using European badgers (Conservation physiology · 2023Article
- Stress in wildlife: comparison of the stress response among domestic, captive, and free-ranging animals.Frontiers in veterinary science · 2023Review
- Physiological Assessment of the Health and Welfare of Domestic Cats-An Exploration of Factors Affecting Urinary Cortisol and Oxytocin.Animals : an open access journal from MDPI · 2022Article
- Stress Concepts and Applications in Various Matrices with a Focus on Hair Cortisol and Analytical Methods.Animals : an open access journal from MDPI · 2022Review
- Selection of appropriate biomatrices for studies of chronic stress in animals: a review.Journal of animal science and technology · 2022Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundChronic stress is implicated in behavioral and health issues in cats, but methods for recognition, evaluation, and measurement of stress are lacking. Cortisol concentration is typically used as an indicator of stress.
objectivesTo evaluate use of an enzyme immunoassay to quantitate hair and nail cortisol concentrations (HCC and NCC) in cats and evaluate associations between HCC and NCC and behavioral, physical, and environmental correlates of chronic stress in cats. ANIMALS: Forty-eight adult, owned or community cats.
methodsCross-sectional study. Nail clippings and hair were collected from cats. Medical history and cat daily lifestyle questionnaires were completed by owners or caretakers. A commercial laboratory performed cortisol extraction and quantification using a validated enzyme immunoassay kit. Correlational and regression analyses were used to evaluate associations between HCC and NCC and behavioral, environmental, and medical factors.
resultsHair and nail cortisol concentrations were significantly associated (r CONCLUSIONS AND CLINICAL IMPORTANCE: The quantification of NCCs might improve identification and evaluation of chronic stress in cats. The variability of HCCs in individual cats warrants caution using this measurement in chronic stress studies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.