Evidence map›Paper›PMID 34704052›Full record

ArticleRSC chemical biology2021

Squaric acid as a new chemoselective moiety for mass spectrometry-based metabolomics analysis of amines.

Weifeng Lin, Zhen Yang, Amanpreet Kaur, Annika Block, Miroslav Vujasinovic, J-Matthias Löhr, Daniel Globisch

Open access · goldAbstract read
In one paragraph

Article in RSC chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Catch-enrich-release approach for amine-containing natural products.Chemical communications (Cambridge, England) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Weifeng LinDepartment of Chemistry-BMC, Science for Life Laboratory, Uppsala University, Box 599 Uppsala SE-75124 Sweden Daniel.globisch@scilifelab.uu.se.ORCID https://orcid.org/0000-0001-8330-7072
Zhen YangDepartment of Chemistry-BMC, Science for Life Laboratory, Uppsala University, Box 599 Uppsala SE-75124 Sweden Daniel.globisch@scilifelab.uu.se.
Amanpreet KaurDepartment of Chemistry-BMC, Science for Life Laboratory, Uppsala University, Box 599 Uppsala SE-75124 Sweden Daniel.globisch@scilifelab.uu.se.ORCID https://orcid.org/0000-0001-8841-8556
Annika BlockDepartment of Chemistry-BMC, Science for Life Laboratory, Uppsala University, Box 599 Uppsala SE-75124 Sweden Daniel.globisch@scilifelab.uu.se.
Miroslav VujasinovicDepartment for Digestive Diseases, Karolinska University Hospital Stockholm Sweden.
J-Matthias LöhrDepartment for Digestive Diseases, Karolinska University Hospital Stockholm Sweden.
Daniel GlobischDepartment of Chemistry-BMC, Science for Life Laboratory, Uppsala University, Box 599 Uppsala SE-75124 Sweden Daniel.globisch@scilifelab.uu.se.ORCID https://orcid.org/0000-0002-4526-5788
Uppsala University · SEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The investigation of microbiome-derived metabolites is important to understand metabolic interactions with their human host. New methodologies for mass spectrometric discovery of undetected metabolites with unknown bioactivity are required. Herein, we introduce squaric acid as a new chemoselective moiety for amine metabolite analysis in human fecal samples.

Identifiers

PMID34704052
PMCPMC8496035
OpenAlexW3195373441

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.