Evidence map›Paper›PMID 34703818›Full record

ReviewJournal of cancer prevention2021

Genomic Approach to the Assessment of Adverse Effects of Particulate Matters on Skin Cancer and Other Disorders and Underlying Molecular Mechanisms.

Nam Gook Kee, Hyun Soo Kim, Hyunjung Choi, Hyoung-June Kim, Young Rok Seo

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of cancer prevention, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Nam Gook KeeDepartment of Life Science, Institute of Environmental Medicine, Dongguk University Biomedi Campus, Goyang, Korea.ORCID https://orcid.org/0000-0002-0760-7804
Hyun Soo KimDepartment of Life Science, Institute of Environmental Medicine, Dongguk University Biomedi Campus, Goyang, Korea.ORCID https://orcid.org/0000-0001-7805-4429
Hyunjung ChoiBioscience Lab., R&D Unit, AmorePacific Corporation, Yongin, Korea.ORCID https://orcid.org/0000-0003-4435-2801
Hyoung-June KimBioscience Lab., R&D Unit, AmorePacific Corporation, Yongin, Korea.ORCID https://orcid.org/0000-0003-0839-1264
Young Rok SeoDepartment of Life Science, Institute of Environmental Medicine, Dongguk University Biomedi Campus, Goyang, Korea.ORCID https://orcid.org/0000-0002-4093-4073
Dongguk University · KRAmorepacific (South Korea) · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Air pollutants are in the spotlight because the human body can easily be exposed to them. Among air pollutants, the particulate matter (PM) represents one of the most serious toxicants that can enter the human body through various exposure routes. PMs have various adverse effects and classified as severe carcinogen by International Agency for Research on Cancer. Their physical and chemical characteristics are distinguished by their size. In this review, we summarized the published information on the physicochemical characteristics and adverse effects of PMs on the skin, including carcinogenicity. Through comparisons of biological networks constructed from relationships discussed in the previous scientific publications, we show it is possible to predict skin cancers and other disorders from particle-size-specific signaling alterations of PM-responsive genes. Our review not only helps to grasp the biological association between ambient PMs and skin diseases including cancer, but also provides new approaches to interpret chemical-gene-disease associations regarding the adverse effects of these heterogeneous particles.

Indexed as

Air pollutantsCarcinogensParticulate matterSkin diseasesToxicogenetics

Identifiers

PMID34703818
PMCPMC8511580
OpenAlexW3205957171

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.