Evidence map›Paper›PMID 34703686›Full record

ArticleCureus2021

Frequency of Cutaneous Disorders in Patients With Celiac Disease.

Kapeel Dev, Fnu Rahul, Kainat Makheja, Jitesh Kumar, Vishal Ahuja, Fnu Ekta, Sahrish Dholia, Sidrah Khan, Abdul Subhan Talpur

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 3 countries.

Kapeel DevInternal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Fnu RahulInternal Medicine, Jinnah Sindh Medical University, Karachi, PAK.
Kainat MakhejaInternal Medicine, Jinnah Sindh Medical University, Karachi, PAK.
Jitesh KumarInternal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Vishal AhujaInternal Medicine, Ghulam Muhammad Mahar Medical College, Sukkur, PAK.
Fnu EktaDivision of Clinical and Translational Research, Larkin Community Hospital, South Miami, USA.
Sahrish DholiaInternal Medicine, Chandka Medical College, Karachi, PAK.
Sidrah KhanInternal Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Abdul Subhan TalpurInternal Medicine, Liaquat University of Medical and Health Sciences, Jamshoro, PAK.
Jinnah Sindh Medical University · PKLarkin Community Hospital · USLiaquat University of Medical & Health Sciences · PKChandka Medical College · PKJinnah Postgraduate Medical Center · PKSree Gokulam Medical College and Research Foundation · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective Celiac disease is an autoimmune multisystem disorder that is triggered by dietary gluten sensitivity in genetically susceptible individuals. It presents with extraintestinal cutaneous manifestations including dermatitis herpetiformis (DH), atopic dermatitis, psoriasis, urticaria, and alopecia areata. Due to the insufficient availability of data, this study aimed to estimate the frequency of cutaneous manifestation in a Pakistani population with celiac disease. Methods This cross-sectional study was conducted from January 2020 to July 2021, and 300 patients with a confirmed diagnosis of celiac disease were enrolled in the study from the internal medicine department of a tertiary care hospital in Pakistan. Celiac disease was confirmed by the presence of immunoglobulin A (IgA) endomysial antibody and IgA tissue transglutaminase antibody. The presence of cutaneous manifestations was assessed with the assistance of a qualified dermatologist and noted in a self-structured questionnaire. Results Overall, the most common cutaneous manifestation was DH (16.0%), whereas the second most common cutaneous manifestation was psoriasis (13.8%). DH was most commonly found among males (18.9%), while psoriasis was more common among females (14.12%). Conclusion Among the various cutaneous presentations in patients with celiac disease, the most common dermatological manifestation was DH. Therefore, patients with cutaneous manifestations should undergo screening for celiac disease.

Indexed as

alopecia areataautoimmune diseaseceliac diseasedermatitis herpetiformispsoriasis

Identifiers

PMID34703686
PMCPMC8529358
OpenAlexW3199598230

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.