Evidence map›Paper›PMID 34703580›Full record

ArticleAnnals of medicine and surgery (2012)2021

Curing the incurable: A case of refractory vasospastic angina.

David Song, Mohamed Abdelghffar, Tasur Seen, Andrew Kim, XiongBin Lin, Saad Ahmad, Talal Almas, Julie Kanevsky

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

David SongDepartment of Internal Medicine Icahn School of Medicine at Mount Sinai - Elmhurst Hospital Center, Elmhurst, NY, USA.
Mohamed AbdelghffarDepartment of Internal Medicine Icahn School of Medicine at Mount Sinai - Elmhurst Hospital Center, Elmhurst, NY, USA.
Tasur SeenDepartment of Internal Medicine Icahn School of Medicine at Mount Sinai - Elmhurst Hospital Center, Elmhurst, NY, USA.
Andrew KimNew York Institute of Technology College of Osteopathic Medicine, Westbury, NY, USA.
XiongBin LinDepartment of Internal Medicine Icahn School of Medicine at Mount Sinai - Elmhurst Hospital Center, Elmhurst, NY, USA.
Saad AhmadDepartment of Internal Medicine Icahn School of Medicine at Mount Sinai - Elmhurst Hospital Center, Elmhurst, NY, USA.
Talal AlmasRoyal College of Surgeons in Ireland, Dublin, Ireland.
Julie KanevskyDepartment of Internal Medicine Icahn School of Medicine at Mount Sinai - Elmhurst Hospital Center, Elmhurst, NY, USA.
Elmhurst Hospital Center · USNew York Institute of Technology · USRoyal College of Surgeons in Ireland · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vasospastic angina (VSA) is the spasm of coronary arteries causing transient myocardial ischemia. VSA is commonly managed with antispasmodic medications including calcium-channel blockers (CCB) and nitrates. When vasospasm is refractory to conventional medications, unconventional treatment modalities may be used for symptomatic relief (Tandon et al., 2019 Feb) [1]. There are several mediators of vasospasm, with serotonin playing a major role. Serotonin is a product of platelet aggregation and has multiple effects on the endothelium, which forms the basis of an unconventional treatment modality that may be used for symptomatic relief of VSA. In this case, a 44 year old female with a history of coronary artery disease (CAD) status post coronary artery bypass graft (CABG) with recent drug-eluting stent (DES) placement was admitted for shortness of breath and chest pain, found to have a positive stress echocardiogram (Echo), and had unremarkable coronary angiography. Given persistent symptoms while on optimal medical therapy and with negative coronary angiography, the diagnosis of refractory VSA was made. Patient was started on a serotonin receptor blocker with improvement of her symptoms.

Indexed as

Coronary artery diseaseSerotonin receptor inhibitorVasospastic angina

Identifiers

PMID34703580
PMCPMC8524098
OpenAlexW3199781609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.