Evidence map›Paper›PMID 34703509›Full record

ArticleRadiology case reports2021

Metastatic choriocarcinoma with hemorrhagic complications and spontaneous ovarian hyperstimulation syndrome: A case report.

Davide Raffaele De Lucia, Anna Castaldo, Valerio D'Agostino, Raffaele Ascione, Ilaria Pesce, Luigi Coppola, Antonio Catelli, Leonardo Radice

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Davide Raffaele De LuciaDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.
Anna CastaldoDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.
Valerio D'AgostinoDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.
Raffaele AscioneDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.
Ilaria PesceDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.
Luigi CoppolaDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.
Antonio CatelliDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.
Leonardo RadiceDepartment of Advanced Biomedical Sciences, University of Naples "Federico II", Via Pansini, 5, Naples 80131, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational choriocarcinoma is a malignant trophoblastic tumor arising from any gestational event, even with a long latency period, generally in the reproductive female. It is associated with a high level of beta-human chorionic gonadotropin. Its primary site is usually the uterus but not all patients have a detectable lesion in this site. Regression of the primary tumor after it has metastasized is not uncommon, and one-third of cases manifest as complications of metastatic disease. In this report we present an uncommon case of gestational choriocarcinoma with lung, liver and jejunal metastases at the time of diagnosis without evidence of pelvic disease, in 34-year-old woman. The main points of interest of our case were the development of the ovarian hyperstimulation syndrome with massive multicystic ovarian enlargement induced by high level of beta-human chorionic gonadotropin and the bleeding of jejunal and liver metastases, due to the high vascularity of the tumor tissue, a condition known as "Choriocarcinoma Syndrome". We will focus on the radiological findings of metastases, bleeding complications and ovarian hyperstimulation syndrome.

Indexed as

b-hCG, Beta Human Chorionic GonadotropinCE-CT, Contrast Enhancement Computed TomographyChoriocarcinoma syndromeFSH, Follicle Stimulating HormoneGestational choriocarcinomaHemorrhagic metastasesHU, Hounsfield UnitHypervascular metastasesLH, Luteinizing HormoneMIP, Maximum Intensity ProjectionMPR, Multiplanar ReconstructionMRI, Magnetic Resonance ImagingOHSS, Ovarian Hyperstimulation SyndromeOvarian hyperstimulation syndromeTSH, Thyroid Stimulating HormoneUS, Ultrasonography

Identifiers

PMID34703509
PMCPMC8526915

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.