Evidence map›Paper›PMID 34703417›Full record

ArticlePrzeglad menopauzalny = Menopause review2021

An enormous pelvic tumor in a 46-year-old woman with an elevated serum CA 125 level, what lies beneath it? Investigation of uterine tumors in postmenopausal women.

Francesk Mulita, Elias Liolis, Dimitrios Kehagias, Levan Tchabashvili, Charalampos Kaplanis, Fotios Iliopoulos, Ioannis Perdikaris, Ioannis Kehagias

Open access · goldAbstract readCase Reports
In one paragraph

Article in Przeglad menopauzalny = Menopause review, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Francesk MulitaDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
Elias LiolisDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
Dimitrios KehagiasDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
Levan TchabashviliDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
Charalampos KaplanisDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
Fotios IliopoulosDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
Ioannis PerdikarisDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
Ioannis KehagiasDepartment of Surgery, General University Hospital of Patras, Rio, Greece.
General University Hospital of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal and pelvic pain with an associated pelvic mass is a very common emergency situation. There is always a management dilemma for most emergency physicians regarding these patients. A 46-year-old postmenopausal woman was admitted to our emergency department (ED) with complaints of massive abdominal distention. Abdominal and pelvis magnetic resonance imaging (MRI) was performed, which revealed a huge pelvic abdominal mass. All tumor markers were within normal limits. However, the ovarian cancer antigen (CA 125) level was elevated. As there was a strong suspicion of malignancy, the patient underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy. Her final histopathology report was suggestive of uterine leiomyoma. Uterine leiomyomas are the most common benign uterine tumors in women. Surgical treatment is the gold standard, especially for older women with severe symptoms and no desire for future fertility. Although the combination of a pelvic tumor and a high-level of CA 125 arouses suspicion of gynecological malignancy, other benign conditions should always be considered in the differential diagnosis. There is limited evidence to support an association between elevated CA 125 levels and uterine fibroids so far. However, conditions such as the coexistence of adenomyosis and tumor size can affect the level of this marker in uterine fibroids.

Indexed as

CA 125leiomyomamenopauseuterine tumor

Identifiers

PMID34703417
PMCPMC8525254
OpenAlexW3207108100

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.